Troglitazone suppresses c-Myc levels in human prostate cancer cells via a PPAR?-independent mechanism.
AuthorsAkinyeke TO, Stewart LV,
JournalCancer Biol Ther
PubMed ID21525782
'Troglitazone is a ligand for the peroxisome proliferator activated receptor gamma (PPAR?) that decreases growth of human prostate cancer cells in vitro and in vivo. However, the mechanism by which troglitazone reduces prostate cancer cell growth is not fully understood. To understand the signaling pathways involved in troglitazone-induced decreases in ... More