Identification of a Novel Transcription Factor, GAGATA-binding Protein, Involved in Androgen-mediated Expression of Prostate-specific Antigen.
AuthorsWang C, Yeung F, Liu PC, Attar RM, Geng J, Chung LW, Gottardis M, Kao C,
JournalJ Biol Chem
PubMed ID12782640
'Prostate-specific antigen (PSA) is the most valuable marker for the evaluation of prostate cancer progression. The expression of PSA is controlled by androgen receptor (AR) through its binding to androgen-response elements (AREs). Several AREs have been identified within the 5.8-kb PSA promoter. The main activity of this 5.8-kb PSA promoter ... More
A simple method using T4 DNA polymerase to clone polymerase chain reaction products.