Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays.
Authors Bernstein Jonathan A; Khodursky Arkady B; Lin Pei-Hsun; Lin-Chao Sue; Cohen Stanley N;
JournalProc Natl Acad Sci U S A
PubMed ID12119387
Much of the information available about factors that affect mRNA decay in Escherichia coli, and by inference in other bacteria, has been gleaned from study of less than 25 of the approximately 4,300 predicted E. coli messages. To investigate these factors more broadly, we examined the half-lives and steady-state abundance ... More