SurePac™ Protein RP MDi™ HPLC Columns
Thermo Scientific™

SurePac™ Protein RP MDi™ HPLC Columns

SurePac Protein RP MDi is a bioinert reversed-phase column engineered for robust HPLC and LC-MS analysis of intact proteins, mAbs and ADCs. It minimizes unspecific interactions with the column hardware, improves recovery, and delivers reproducible, high-resolution separations for sensitive therapeutic proteins workflows.
Have Questions?
Change viewbuttonViewtableView
Catalog NumberDiameter (Metric)Length (Metric)
43722-050332300 μm50 mm
43722-0221322.1 mm20 mm
43722-0521322.1 mm50 mm
43722-1021322.1 mm100 mm
Catalog number 43722-050332
Price (CNY)
12,602.54
Each
Diameter (Metric):
300 μm
Length (Metric):
50 mm
Price (CNY)
12,602.54
Each
Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC columns deliver high-resolution, reproducible separations for monoclonal antibodies, antibody subunits, and ADCs across development and QC workflows. Built on monodisperse, supermacroporous polymeric particle technology with bio-inert hardware, they provide stable performance under elevated temperatures used in LC-MS, enabling consistent peak shape, reliable resolution, and durable operation for scalable protein analysis.
  • Designed for reversed-phase protein separations
  • Engineered for intact proteins, mAbs and ADCs, delivering reliable retention and selectivity across a wide range of molecular weights.
  • Bioinert, metal-free flow path
  • Optimized for LC-MS protein workflows
  • Fully compatible with MS-friendly mobile phases, enabling sensitive and reproducible detection of intact proteins and peptide maps.
  • Robust stationary phase for high-temperature operation
  • Maintains stable performance under elevated temperatures and high organic conditions, supporting fast gradients and durable methods.
  • Excellent peak shape and resolution
  • Delivers sharp, symmetrical peaks and effective separation of protein variants, isoforms, and closely related species.
  • Reproducible performance across columns and batches
  • Tight manufacturing controls ensure consistent results and smooth method transfer between instruments and laboratories.
  • Suitable for development and routine analysis
  • Supports method development, characterization, and QC workflows, reducing the need for multiple column chemistries.
  • Compatible with UHPLC and HPLC systems
Specifications
Column FormatAnalytical
Flow Rate1 to 12 μL/min.
Max. Pressure8000 psi (552 bar)
Packing MaterialPolymeric
Stationary PhasePoly-DVB
Temperature5°C to 90°C
Diameter (Metric)300 μm
Length (Metric)50 mm
Particle Size2.5 μm
Pore SizeProprietary supermacroporous
pH2 to 12
Unit SizeEach