Cyclic strain alters the expression and release of angiogenic factors by human tendon cells.
AuthorsMousavizadeh R, Khosravi S, Behzad H, McCormack RG, Duronio V, Scott A,
Journal
PubMed ID24824595
Angiogenesis is associated with the tissue changes underlying chronic overuse tendinopathy. We hypothesized that repetitive, cyclic loading of human tendon cells would lead to increased expression and activity of angiogenic factors. We subjected isolated human tendon cells to overuse tensile loading using an in vitro model (1 Hz, 10% equibiaxial ... More