Accucore™ PREP XL C18 HPLC Columns

Build off of conventional HPLC methods for your scale up purification needs by using Thermo Scientific™ Accucore™ XL C18 preparative HPLC Columns. Rugged 4μm solid-core particles ensure high-efficiencies within low pressure limits requirements. The high bonded phase coverage delivers optimal retention of a comprehensive range of non-polar analytes throughout numerous applications. Our columns come in a wide range of dimensions and an option for XtendedLife hardware which improves column lifetime by maintaining a uniform packed bed.

Optimal Selectivity for Nonpolar Compounds

• Hydrophobic interaction mechanism.
• C18 (USP L1) selectivity.

High-Efficiency Separations for Enhanced Resolution and Sensitivity

• Core-enhanced technology 4μm particles and narrow particle size distribution reduce band broadening and improve separation efficiencies for conventional HPLC methods.
• High surface coverage of silica minimizes secondary interactions and peak tailing.

Preparative HPLC Column Hardware Options - based on column inner diameter (i.d.) and column performance needs.

Standard Threaded and Standard Flange Hardware

• Designed for standard applications, expertly packed and robustly designed to provide versatile products for routine use.
• Standard threaded hardware for column i.d. < 40mm.
• Standard flange hardware for column i.d. ≥ 40mm.
• Standard hardware can be modified on request to be compatible with SFC.

XtendedLife Hardware

• Improves column lifetime by incorporating an internal Dynamic Axial Compression (DAC) system, ensuring the media bed is continuously packed tightly.
• Compatible with SFC and is available in dimensions up to 50mm i.d.

Preparative Guards are a proven and cost effective way to extend the lifetime of your prep column. Our preparative guard columns require the use of a preparative guard holder.

Customer Specific Orders

• If there is a Thermo Scientific stationary phase you are currently using and would like to obtain in a preparative scale not shown or would like to discuss a specific column dimension, we would be happy to discuss your requirements.
• Please contact your local sales representative for Customer Specific Orders.
• Custom built columns are not eligible for returns.