A-23187游离酸（卡西霉素）
A-23187游离酸（卡西霉素）
引用和文献 (397)
Invitrogen™

A-23187游离酸（卡西霉素）

Ca2+ 离子载体 A-23187 通常用于荧光 Ca2+ 指示剂的原位校准、平衡细胞内外 Ca2+ 浓度以及便于 Mn2+了解更多信息
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货号数量
A149310 mg
货号 A1493
价格（CNY)
2,855.00
飞享价
Ends: 31-Dec-2025
3,745.00
共减 890.00 (24%)
Each
添加至购物车
数量:
10 mg
价格（CNY)
2,855.00
飞享价
Ends: 31-Dec-2025
3,745.00
共减 890.00 (24%)
Each
添加至购物车
Ca2+ 离子载体 A-23187 通常用于荧光 Ca2+ 指示剂的原位校准、平衡细胞内外 Ca2+ 浓度以及便于 Mn2+ 进入细胞而使细胞内染料荧光淬灭。虽然 A-23197 的内源性荧光很强，无法与紫外光可激发的 fura-2、indo-1 和 quin-2 等钙指示剂配合使用，但是它适合与可见光可激发的 fluo-4、fluo-3、Calcium Green 和 rhod-2 等指示剂配合使用。A-23187 也可用于平衡细胞内外 Mg2+ 浓度，使其适用于校准 Mg2+ 指示剂。

了解更多有关离子指示剂（包括钙、钾、pH 值和膜电位指示剂）的信息›

仅供科研使用。不可用于诊断程序。
规格
检测方法荧光
适用于（设备）荧光显微镜、流式细胞仪、荧光计、荧光成像仪
指示器钙指示剂
分子式C29H37N3O6
数量10 mg
建议的储存条件在冷冻冰箱（-5°C 至 -30°C）中避光储存。
运输条件室温
物理形态实心
产品类型卡西霉素
Unit SizeEach

引用和文献 (397)

引用和文献
Abstract
Flow cytometric measurement of the production of reactive oxygen intermediate in activated rat mast cells.
Authors:Tsinkalovsky OR, Laerum OD
Journal:APMIS
PubMed ID:7520710
The production of reactive oxygen intermediates (ROI) in compound 48/80- or calcium ionophore A 23187- activated pleural or peritoneal mast cells was monitored using flow cytometry and the fluorescence indicator dihydrorhodamine 123 (a derivate of rhodamine 123). Mast cell degranulation and ROI production were estimated by flow cytometric fluorescence and ... More
Inhibition of NADPH oxidase activation by 4-(2-aminoethyl)-benzenesulfonyl fluoride and related compounds.
Authors:Diatchuk V, Lotan O, Koshkin V, Wikstroem P, Pick E
Journal:J Biol Chem
PubMed ID:9148950
The elicitation of an oxidative burst in phagocytes rests on the assembly of a multicomponental complex (NADPH oxidase) consisting of a membrane-associated flavocytochrome (cytochrome b559), representing the redox element responsible for the NADPH-dependent reduction of oxygen to superoxide (O-2), two cytosolic components (p47(phox), p67(phox)), and the small GTPase Rac (1 ... More
Exocytotic insertion of calcium channels constrains compensatory endocytosis to sites of exocytosis.
Authors:Smith RM, Baibakov B, Ikebuchi Y, White BH, Lambert NA, Kaczmarek LK, Vogel SS
Journal:J Cell Biol
PubMed ID:10684256
'Proteins inserted into the cell surface by exocytosis are thought to be retrieved by compensatory endocytosis, suggesting that retrieval requires granule proteins. In sea urchin eggs, calcium influx through P-type calcium channels is required for retrieval, and the large size of sea urchin secretory granules permits the direct observation of ... More
Involvement of nuclear factor of activated T cells activation in UV response. Evidence from cell culture and transgenic mice.
Authors:Huang C, Mattjus P, Ma WY, Rincon M, Chen NY, Brown RE, Dong Z
Journal:J Biol Chem
PubMed ID:10734048
'Mammalian cells respond to UV radiation by signaling cascades leading to activation of transcription factors, such as activated protein 1, NFkappaB, and p53, a process known as the "UV response." Nuclear factor of activated T cells (NFAT) was first identified as an inducible nuclear factor in immune response and subsequently ... More
Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506.
Authors:Peters D, Tsuchida M, Manthei ER, Alam T, Cho CS, Knechtle SJ, Hamawy MM
Journal:Blood
PubMed ID:10779414
'The activation of blood cells, including T cells, triggers intracellular signals that control the expression of critical molecules, including cytokines and cytokine receptors. We show that T-cell receptor (TCR) ligation increases the cellular level of the protein linker for activation of T cells (LAT), a molecule critical for T-cell development ... More
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