CTS™ OpTmizer™ T 细胞扩增 SFM,无酚红,瓶装规格
CTS™ OpTmizer™ T 细胞扩增 SFM,无酚红,瓶装规格
Gibco™

CTS™ OpTmizer™ T 细胞扩增 SFM,无酚红,瓶装规格

Gibco CTS OpTmizer T 细胞扩增 SFM 支持人 T 淋巴细胞的生长和扩增。它是一种完全无血清了解更多信息
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货号 A3705001
价格(CNY)
3,034.00
Each
添加至购物车
价格(CNY)
3,034.00
Each
添加至购物车
Gibco CTS OpTmizer T 细胞扩增 SFM 支持人 T 淋巴细胞的生长和扩增。它是一种完全无血清、无异种成分的培养基,由 CTS OpTmizer T 细胞扩增基础培养基和 CTS OpTmizer T 细胞扩增补充剂组成,在使用前混合在一起。

CTS OpTmizer T 细胞扩增 SFM 提供含酚红和不含酚红两种规格。此版本的 CTS OpTmizer SFM 不含酚红,提供瓶装和袋装两种规格。

CTS OpTmizer T 细胞扩增 SFM 的特点包括:
•支持高密度 T 细胞培养(>4 x 106 个 CD3+ T 细胞/mL)
• 支持使用 Dynabeads 磁珠、可溶性抗体和刺激抗体呈递细胞方案活化 T 细胞
• 使用该培养基培养的 T 细胞与使用含常规人 AB 血清的培养基培养的 T 细胞具有相似的表型、功能(例如,细胞因子分泌表达谱)和活力
• 支持与补充人血清的培养基相似的 T 细胞表型
• 研究显示,CART-19 细胞在补充 CTS 免疫细胞血清替代物 (ICSR) 的培养基中生长时,效力和持续性有所提高

证明功能性性能
在 CTS OpTmizer T 细胞扩增 SFM(含或不含人血清)中生长的细胞在多克隆活化 T 细胞中显示出良好的细胞因子生成表达谱。CTS OpTmizer T 细胞扩增 SFM 可维持所需的 CD62L+ 中央记忆 T 细胞表型。

按照 GMP 生产
CTS OpTmizer T 细胞扩增 SFM 的主要生产工厂已经在 FDA 注册,并具有 ISO13485 认证的质量管理体系。生产方法和质控措施符合现行医疗器械药品生产质量管理规范(21 CFR 第 820 部分)。具有替代生产工厂,有助于确保供应安全,从而降低风险。

多功能性
CTS OpTmizer T 细胞扩增 SFM 已广泛用于多种临床 T 细胞研究应用,包括 CAR T 细胞的培养。它适用于多种培养形式,包括培养瓶、培养袋和摇摆式生物反应器。CTS OpTmizer T 细胞扩增 SFM 设计用于支持培养的人 T 细胞的扩增,不需额外补充血清。当补充 CTS 免疫细胞血清替代物时,通常会观察到性能提高。

产品包装规格
CTS OpTmizer T 细胞扩增 SFM 包含两种组分:1 升 CTS OpTmizer T 细胞扩增基础培养基和 26 mL CTS OpTmizer T 细胞扩增辅助浓缩培养基,混合在一起就形成完全培养基。可提供完整的溯源性证明文件,例如原产地证书和分析证书。
规格
细胞类型T 细胞
产品线OpTmizer™
产品类型无血清培养基 (SFM)
数量1000 mL
运输条件室温
不加添加剂无酚红
Unit SizeEach

常见问题解答 (FAQ)

What is CTS?

The Gibco Cell Therapy Systems (CTS) portfolio of cell and gene therapy products are GMP manufactured, safety tested, and backed by regulatory documentation to support your transition from discovery through clinical and commercial manufacturing. Through our CTS solutions, we are committed to helping customers streamline therapeutic development, minimize risk, and ease the burden on their quality systems. Learn more here.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Do you offer the CTS OpTmizer Expansion Basal Medium and CTS OpTmizer Expansion Supplement (included in the CTS OpTmizer T-Cell Expansion SFM (Cat. No. A3705001)) as stand-alone products?

No, the CTS OpTmizer Expansion Basal Medium and CTS OpTmizer Expansion Supplement are not sold separately.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Is there a difference in formulation of the CTS OpTmizer T Cell Expansion SFM between the bottle and bag packaging formats?

The bottle and bag packaging formats of the medium have the same formulation.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Can I use CTS OpTmizer T Cell Expansion SFM for culture and expansion of mouse T cells? If not, which medium would you recommend?

We have not tested this medium on mouse T cells. If you're looking for a serum-free medium to culture mouse T cells, you can try AIM V Medium (Cat. No. 12055083 or 12055091). For mouse cells, we recommend adding 50 µM beta-mercaptoethanol (Cat. No. 21985023).

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.

Can GlutaMAX be used instead of Glutamine to supplement CTS OpTmizer T-Cell Expansion SFM?

GlutaMAX cannot replace Glutamine because cells may not initially use GlutaMAX so that T cells cannot grow. We recommend adding 4 mM GlutaMAX and 2 mM Glutamine (as stated in the manual) into the CTS OpTmizer T-Cell Expansion SFM if GlutaMAX is needed.

Find additional tips, troubleshooting help, and resources within our Cell Culture Support Center.