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Invitrogen
CGRP Monoclonal Antibody (4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
ABS 026-04-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
4
Immunogen
Synthetic peptide corresponding to residues 19-37 of human alpha-CGRP.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.98 mg/mL
Amount
392 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
ABS 026-04-02 detects CGRP alpha in human samples.
ABS 026-04-02 has been successfully used in ELISA and immunohistochemistry procedures.
Target Information
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: alpha-type CGRP; calcitonin; calcitonin 1; calcitonin gene related protein; calcitonin gene-related peptide I; calcitonin precursor; calcitonin/calcitonin-related polypeptide, alpha; katacalcin; MGC126648; RAT calcitonin; unnamed protein product
Gene Aliases: CALC1; CGRP; CGRP-alpha; CGRP-I; CGRP1; CT; KC; PCT
UniProt ID: (Human) P01258
Entrez Gene ID: (Human) 796
response to yeast
endothelial cell proliferation
vasculature development
neurological system process involved in regulation of systemic arterial blood pressure
G-protein coupled receptor internalization
monocyte chemotaxis
protein phosphorylation
leukocyte cell-cell adhesion
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
embryo implantation
regulation of blood pressure
negative regulation of calcium ion transport into cytosol
antibacterial humoral response
antifungal humoral response
receptor internalization
activation of protein kinase activity
positive regulation of interleukin-1 alpha production
positive regulation of interleukin-8 production
vasodilation
endothelial cell migration
innate immune response
positive regulation of macrophage differentiation
negative regulation of osteoclast differentiation
negative regulation of blood pressure
negative regulation of bone resorption
negative regulation of transcription, DNA-templated
negative regulation of smooth muscle contraction
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
regulation of cytosolic calcium ion concentration
antimicrobial humoral immune response mediated by antimicrobial peptide
cellular response to tumor necrosis factor
calcitonin family receptor signaling pathway
amylin receptor 1 signaling pathway
amylin receptor 2 signaling pathway
cellular response to nerve growth factor stimulus
calcitonin gene-related peptide receptor signaling pathway
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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