On the prospect of serum exosomal miRNA profiling and protein biomarkers for the diagnosis of ascending aortic dilatation in patients with bicuspid and tricuspid aortic valve.
AuthorsGallo A, Agnese V, Coronnello C, Raffa GM, Bellavia D, Conaldi PG, Pilato M, Pasta S
JournalInt J Cardiol
PubMed ID30297190
To determine the impact of circulating miRNA and protein activity on the severity of ascending aortic dilatation in patients with bicuspid (BAV) and tricuspid aortic valve (TAV). ... More
Effect of omalizumab on bronchoalveolar lavage matrix metalloproteinases in severe allergic asthma.
AuthorsZastrzezynska W, Bazan-Socha S, Przybyszowski M, Gawlewicz-Mroczka A, Jakiela B, Plutecka H, Zareba L, Musial J, Okon K, Sladek K, Soja J
JournalJ Asthma
PubMed ID33764254
Airway inflammation in asthma is accompanied by reconstruction of the bronchial wall extracellular matrix that most likely occurs with a contribution of matrix metalloproteinases (MMPs). Recently we have reported that omalizumab may decrease reticular basement membrane (RBM) thickness together with fibronectin deposits in asthmatic airways, although mechanisms involved are unknown. ... More