Aneuploid mosaicism in the developing and adult cerebellar cortex.
AuthorsWestra JW, Peterson SE, Yung YC, Mutoh T, Barral S, Chun J,
JournalJ Comp Neurol
PubMed ID18273885
'Neuroprogenitor cells (NPCs) in several telencephalic proliferative regions of the mammalian brain, including the embryonic cerebral cortex and postnatal subventricular zone (SVZ), display cell division "defects" in normal cells that result in aneuploid adult progeny. Here, we identify the developing cerebellum as a major, nontelencephalic proliferative region of the vertebrate ... More