Search
Citations & References (7)
Invitrogen™
HCS LipidTOX™ Red Phospholipidosis Detection Reagent (1000X), for cellular imaging
The HCS LipidTOX™ Red phospholipidosis detection reagent was developed to characterize the potentially toxic side effects of compounds on lipidRead more
| Catalog Number | Quantity |
|---|---|
| H34351 | 1 each |
Catalog number H34351
Price (CNY)
5,819.00
Each
Quantity:
1 each
Price (CNY)
5,819.00
Each
The HCS LipidTOX™ Red phospholipidosis detection reagent was developed to characterize the potentially toxic side effects of compounds on lipid metabolism in mammalian cell lines. This reagent is easily detected by fluorescence microscopy or an HCS reader equipped with filters that can detect excitation/emission maxima ∼595/615 nm. LipidTOX™ phospholipidosis detection reagents do not affect the normal growth of cells, and the staining observed after incubation in live cells is maintained after formaldehyde fixation. This probe is compatible with the HCS LipidTOX™ neutral lipid stains (H34475, H34476, and H34477).
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Detection MethodFluorescence
Dye TypeOther Label(s) or Dye(s)
Format96-well plate
Quantity1 each
Shipping ConditionRoom Temperature
For Use With (Equipment)High Content Analysis Instrument
Product LineLipidTOX
Product TypePhospholipidosis Detection Reagent
Unit SizeEach
Contents & Storage
Store in freezer -5°C to -30°C and protect from light.
Citations & References (7)
Citations & References
Abstract
Fluorescent high-content imaging allows the discrimination and quantitation of E-LDL-induced lipid droplets and Ox-LDL-generated phospholipidosis in human macrophages.
Journal:Cytometry A
PubMed ID:20014301
'Macrophage foam cells formed during uptake of atherogenic lipoproteins are a hallmark of atherosclerotic lesion development. In this study, human macrophages were incubated with two prototypic atherogenic LDL modifications enzymatically degraded LDL (E-LDL) and oxidized LDL (Ox-LDL) prepared from the same donor LDL. To detect differences in macrophage lipid storage,
In vitro detection of drug-induced phospholipidosis using gene expression and fluorescent phospholipid based methodologies.
Journal:Toxicol Sci
PubMed ID:17567588
'Phospholipidosis (PLD) is characterized by the excessive intracellular accumulation of phospholipids. It is well established that a large number of cationic amphiphilic drugs have the potential to induce PLD. In the present study, we describe two facile in vitro methods to determine the PLD-inducing potential of a molecule. The first
Comparative analysis of lipotoxicity induced by endocrine, pharmacological, and innate immune stimuli in rat basophilic leukemia cells.
Journal:J Immunotoxicol
PubMed ID:25539471
Time-restricted feeding delays the emergence of the age-associated, neoplastic-prone tissue landscape.
Journal:Aging (Albany NY)
PubMed ID:31188781
Silencing of solute carrier family 13 member 5 disrupts energy homeostasis and inhibits proliferation of human hepatocarcinoma cells.
Journal:J Biol Chem
PubMed ID:28655760