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引用和文献 (34)
Invitrogen™
Image-IT™ LIVE Green 活性氧检测试剂盒（用于显微镜检查）
Image-iT™ LIVE Green 活性氧 (ROS) 检测试剂盒提供了活细胞中 ROS 检测所必需的关键试剂。测定基于 5-了解更多信息
| 货号 | 数量 |
|---|---|
| I36007 | 1 Kit |
货号 I36007
价格（CNY)
6,446.00
Each
数量:
1 Kit
价格（CNY)
6,446.00
Each
Image-iT™ LIVE Green 活性氧 (ROS) 检测试剂盒提供了活细胞中 ROS 检测所必需的关键试剂。测定基于 5-（和 -6）-羧基-2',7'-二氯二氢荧光素二乙酸酯（羧基-H2DCFDA），这是活细胞中可靠的 ROS 荧光标志物。除羧基-H2DCFDA 外，试剂盒还提供了 ROS 生成叔丁基过氧化氢（tert-butyl hydroperoxide，以下简称 TBHP）的常见诱导剂（作为阳性对照）和蓝色荧光、细胞可穿透核酸染料 Hoechst 33342。
仅供科研使用。不可用于诊断程序。
规格
数量1 Kit
产品线Image-iT
产品类型ROS Detection Kit
Unit SizeEach
引用和文献 (34)
引用和文献
Abstract
Immunoglobulin light chains generate hydrogen peroxide.
Journal:J Am Soc Nephrol
PubMed ID:17360948
'As low molecular weight proteins, restriction from glomerular filtration is minimized, permitting significant amounts of Ig light chains to be endocytosed into the proximal tubule epithelium, particularly in plasma cell dyscrasias. Recent studies have shown that this effect of concentrating light chains within the proximal tubule alters cell function. This
Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 kinase isoforms.
Journal:J Biol Chem
PubMed ID:16407188
'From human and animal studies, estrogen is known to protect the myocardium from an ischemic insult. However, there is limited knowledge regarding mechanisms by which estrogen directly protects cardiomyocytes. In this report, we employed an in vitro model, in which cultured rat cardiomyocytes underwent prolonged hypoxia followed by reoxygenation (H/R),
24-dehydrocholesterol reductase/seladin-1: a key protein differentially involved in adrenocorticotropin effects observed in human and rat adrenal cortex.
Journal:Endocrinology
PubMed ID:19520779
'DHCR24 (24-dehydrocholesterol reductase), or seladin-1, is one of the most expressed genes in the adrenal gland. Because the rat and human adult adrenal cortex differ in their respective functional properties, the aim of the present study was to verify whether seladin-1 may be differentially involved in basal and ACTH-stimulated steroidogenesis
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
Journal:J Biol Chem
PubMed ID:19386607
'Tubacin is a small molecule inhibitor of histone deacetylase 6 and blocks aggresome activity. We found that Epstein-Barr virus (EBV)-positive Burkitt lymphoma (BL) cells were generally killed by lower doses of tubacin than EBV-transformed lymphoblastoid cells (LCLs) or EBV-negative BL cells. Tubacin induced apoptosis of LCLs, which was inhibited by
HER-2 signaling, acquisition of growth factor independence, and regulation of biological networks associated with cell transformation.
Journal:Cancer Res
PubMed ID:20736364
'Activated oncogenes are the dominant drivers of malignant progression in human cancer, yet little is known about how the transformation from proto-oncogene to activated oncogene drives the expression of transformed phenotypes. An isogenic model of HER-2-mediated transformation of human mammary epithelial cells was used along with HER-2-amplified human breast cancers