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Invitrogen
Cytokeratin 8 Monoclonal Antibody (C-43)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA1-19037
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Sheep,
Pig,
Rabbit
已发表种属
Dog,
Goat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
C-43
抗原
Cytoskeleton preparation from HeLa human cervix carcinoma cell line
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts with cytokeratin 8 (52.5 kDa intracellular antigen). Cytokeratins are members of intermediate filaments subfamily represented in epithelial tissues.
This antibody will not cross-react with hamster, mouse, Xenopus, rat or chicken.
靶标信息
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CK-8; cytokeratin 8; cytokeratin-8; cytokeratin-A; K8; KERA; keratin 8, type II; type II cytokeratin A (no.8); type-II keratin Kb8; unnamed protein product
基因别名: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO; KRT2-8
UniProt ID: (Bovine) P05786, (Human) P05787
Entrez Gene ID: (Rabbit) 100348891, (Bovine) 281269, (Human) 3856, (Pig) 100152077, (Sheep) 101110495
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