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Non-reducing conditions are recommended for Western blot applications. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.
Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Auberger B antigen; B-CAM cell surface glycoprotein; Basal cell adhesion molecule; CD239; F8/G253 antigen; Lutheran antigen; Lutheran blood group glycoprotein
Gene Aliases: BCAM; LU; MSK19
Entrez Gene ID: (Human) 4059
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