Search
Invitrogen
MARK2 Recombinant Rabbit Monoclonal Antibody (24GB675)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 4
MARK2 Antibody (MA5-57463) in ICC/IF
Immunocytochemical staining of MARK2 in HT-1080 cells using MARK2 Recombinant Monoclonal Antibody (Product # MA5-57462) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; MARK2 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-57463
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
24GB675
抗原
A synthesized peptide derived from human MARK2 (aa 700-788)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
2 mg/mL
规格
40 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
RRID
靶标信息
MARK2 is a serine/threonine protein kinase involved in the control of cell polarity and microtubule stability. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: ELKL motif kinase; ELKL motif kinase 1; EMK-1; MAP/microtubule affinity-regulating kinase 2; MGC99619; OTTHUMP00000218338; OTTHUMP00000218339; OTTHUMP00000218340; OTTHUMP00000218343; Par-1b; PAR1 homolog; PAR1 homolog b; Serine/threonine-protein kinase MARK2
基因别名: Emk; EMK-1; EMK1; MARK2; Par-1; Par-1b
UniProt ID: (Mouse) Q05512
Entrez Gene ID: (Mouse) 13728
nucleotide binding
magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
ATP binding
lipid binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
poly(A) RNA binding
metal ion binding
tau-protein kinase activity
non-receptor serine/threonine protein kinase
neuron migration
protein phosphorylation
multicellular organism development
positive regulation of neuron projection development
Wnt signaling pathway
phosphorylation
establishment of cell polarity
cell differentiation
intracellular signal transduction
establishment or maintenance of epithelial cell apical/basal polarity
protein autophosphorylation
regulation of axonogenesis
regulation of cytoskeleton organization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
