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Invitrogen
ITPA Polyclonal Antibody
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图: 1 / 6
ITPA Antibody (PA5-102393) in ICC/IF
Immunofluorescent analysis of ITPA in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and ITPA polyclonal antibody (Product # PA5-102393) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102393
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human ITPA(Accession Q9BY32), corresponding to amino acid residues R130-R180.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total ITPA.
靶标信息
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Inosine triphosphate pyrophosphatase; inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; ITPase; ITPase {ECO:0000255|HAMAP-Rule:MF_03148}; My049 protein; Non-canonical purine NTP pyrophosphatase; non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Non-standard purine NTP pyrophosphatase; non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; NTPase; NTPase {ECO:0000255|HAMAP-Rule:MF_03148}; nucleoside triphosphate pyrophosphatase; Nucleoside-triphosphate diphosphatase; nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Nucleoside-triphosphate pyrophosphatase; nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}; Putative oncogene protein hlc14-06-p; XTP/dITP diphosphatase
基因别名: 2010016I08Rik; AU020102; C20orf37; Itp; ITPA; My049; OK/SW-cl.9
UniProt ID: (Rat) D3ZW55, (Mouse) Q9D892
Entrez Gene ID: (Rat) 311422, (Mouse) 16434
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