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Invitrogen
USP9X Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106448
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human USP9X(Accession Q93008), corresponding to amino acid residues M1-P47.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total USP9X.
Target Information
USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity. USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme FAF-X; Fat facets homolog; Fat facets in mammals; Fat facets protein-related, X-linked; fats facets protein related, X; hFAM; probable ubiquitin carboxyl-terminal hydrolase FAF-X; Ubiquitin carboxyl-terminal hydrolase 9X; Ubiquitin carboxyl-terminal hydrolase FAM; ubiquitin specific peptidase 9, X chromosome; ubiquitin specific protease 9 SSSRF- isoform; ubiquitin specific protease 9, X chromosome; Ubiquitin thioesterase FAF-X; ubiquitin thiolesterase FAF-X; Ubiquitin-specific protease 9, X chromosome; Ubiquitin-specific-processing protease FAF-X
Gene Aliases: 5730589N07Rik; AA407302; AA407699; AL022658; AL022749; DFFRX; FAF-X; Fafl; FAM; RGD1560056; USP9; USP9X
UniProt ID: (Mouse) P70398
Entrez Gene ID: (Mouse) 22284, (Rat) 363445
in utero embryonic development
neuron migration
proteolysis
ubiquitin-dependent protein catabolic process
cell cycle
chromosome segregation
mitotic nuclear division
transforming growth factor beta receptor signaling pathway
post-embryonic development
protein deubiquitination
cerebellar cortex structural organization
hippocampus development
BMP signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
axon extension
cell division
regulation of proteasomal protein catabolic process
cellular response to transforming growth factor beta stimulus
neuron projection extension
cell migration
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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