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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total SMCHD1.
Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the de novo methyltransferase DNMT3B. Required for DUX4 silencing in somatic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: SMC hinge domain-containing protein 1; structural maintenance of chromosomes flexible hinge domain containing 1; Structural maintenance of chromosomes flexible hinge domain-containing protein 1
基因别名: 4931400A14Rik; AW554188; KIAA0650; mKIAA0650; MommeD1; RGD1307234; SMCHD1
UniProt ID: (Mouse) Q6P5D8
Entrez Gene ID: (Rat) 316732, (Mouse) 74355