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Invitrogen
FZD1 Polyclonal Antibody
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FZD1 Antibody (PA5-86484) in WB
Western blot analysis of PTGER2 in Lane 1: H9C2 whole cell lysate (40 µg), Lane 2: CT26 whole cell lysate (40 µg), Lane 3: Panc1 whole cell lysate (40 µg), Lane 4: A549 whole cell lysate (40 µg), Lane 5: HepG2 whole cell lysate (40 µg). Sample was incubated with PTGER2 polyclonal antibody (Product # PA5-86484) using a 1:500 dilution.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-86484
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide, corresponding to amino acids 22-76 of Human Frizzled-1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Purity is > 95% by SDS-PAGE.
靶标信息
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chfz-1; Dfrizzled-1; DKFZp564G072; Drosophila polarity gene (frizzled) homologue; Drosophila polarity gene homolog 1; FLJ95923; frizzled; frizzled 1; frizzled family receptor 1; Frizzled-1; Fz receptor 1; Fz-1; FzE1; mFz1; rFz1; Xfrizzled-1
基因别名: AW227548; FZ-1; Fz1; FZD1
UniProt ID: (Mouse) O70421
Entrez Gene ID: (Rat) 58868, (Mouse) 14362
G-protein coupled receptor activity
receptor binding
frizzled binding
protein binding
Wnt-protein binding
PDZ domain binding
identical protein binding
protein homodimerization activity
Wnt-activated receptor activity
protein heterodimerization activity
signal transducer activity
transmembrane signaling receptor activity
transmembrane signal receptor
positive regulation of protein phosphorylation
membranous septum morphogenesis
muscular septum morphogenesis
outflow tract morphogenesis
G-protein coupled receptor signaling pathway
cell-cell signaling
Wnt signaling pathway
negative regulation of BMP signaling pathway
epithelial cell differentiation
negative regulation of catenin import into nucleus
autocrine signaling
non-canonical Wnt signaling pathway
response to drug
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
regulation of osteoblast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
lung alveolus development
positive regulation of sequence-specific DNA binding transcription factor activity
hard palate development
canonical Wnt signaling pathway
ventricular septum morphogenesis
cellular response to vitamin D
cellular response to growth factor stimulus
cellular response to peptide hormone stimulus
negative regulation of canonical Wnt signaling pathway
planar cell polarity pathway involved in neural tube closure
signal transduction
cell surface receptor signaling pathway
multicellular organism development
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