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引用和文献 (106)
Invitrogen™
Nonyl Acridine Orange（吖啶橙 10-溴壬烷）
Nonyl acridine orange 可在线粒体中良好保留，因而可作为一种有效探针，在细胞分离期间及细胞融合后跟踪线粒体状态。据报道，线粒体的摄取不依赖膜电位，不同于其他线粒体探针。故无论其是否处于带电状态，在高浓度下均具有毒性，且明显与所有线粒体中的心磷脂结合。该衍生物已用于线粒体流式细胞分析、多药物耐药性鉴定以及凋亡期间线粒体质量变化测定。了解更多信息
| 货号 | 数量 |
|---|---|
| A1372 | 100 mg |
货号 A1372
价格（CNY)
1,622.00
飞享价
Ends: 31-Dec-2025
2,198.00共减 576.00 (26%)
Each
数量:
100 mg
价格（CNY)
1,622.00
飞享价
Ends: 31-Dec-2025
2,198.00共减 576.00 (26%)
Each
Nonyl acridine orange 可在线粒体中良好保留，因而可作为一种有效探针，在细胞分离期间及细胞融合后跟踪线粒体状态。据报道，线粒体的摄取不依赖膜电位，不同于其他线粒体探针。故无论其是否处于带电状态，在高浓度下均具有毒性，且明显与所有线粒体中的心磷脂结合。该衍生物已用于线粒体流式细胞分析、多药物耐药性鉴定以及凋亡期间线粒体质量变化测定。
仅供科研使用。不可用于诊断程序。
规格
颜色橙色
检测方法荧光
适用于（设备）荧光显微镜
数量100 mg
运输条件室温
标签类型Fluorescent Dye
产品类型壬基吖啶橙
亚细胞定位线粒体Mitochondria
Unit SizeEach
内容与储存
室温避光储存。
引用和文献 (106)
引用和文献
Abstract
Analysis of mitochondria isolated from single cells.
Journal:Analytical and bioanalytical chemistry
PubMed ID:16937092
Human epidermal cells progressively lose their cardiolipins during ageing without change in mitochondrial transmembrane potential.
Journal:Mech Ageing Dev
PubMed ID:7745994
Mitochondria dysfunction is considered to be a major cause of the modifications that occur during cell ageing. For this reason, cardiolipin, a suitable marker of the chondriome, as well as the mitochondrial transmembrane potential were examined in keratinocytes obtained from 9- to 75-year-old women. The study was carried out by
Tamoxifen but not 4-hydroxytamoxifen initiates apoptosis in p53(-) normal human mammary epithelial cells by inducing mitochondrial depolarization.
Journal:J Biol Chem
PubMed ID:11094056
'Despite the widespread clinical use of tamoxifen as a breast cancer prevention agent, the molecular mechanism of tamoxifen chemoprevention is poorly understood. Abnormal expression of p53 is felt to be an early event in mammary carcinogenesis. We developed an in vitro model of early breast cancer prevention to investigate how
Sortase A localizes to distinct foci on the Streptococcus pyogenes membrane.
Journal:Proc Natl Acad Sci U S A
PubMed ID:19017791
'Cell wall peptidoglycan-anchored surface proteins are essential virulence factors in many gram-positive bacteria. The attachment of these proteins to the peptidoglycan is achieved through a transpeptidation reaction, whereby sortase cleaves a conserved C-terminal LPXTG motif and covalently attaches the protein to the peptidoglycan precursor lipid II. It is unclear how
Methods for assessing autophagy and autophagic cell death.
Journal:Methods Mol Biol
PubMed ID:18425442
'Autophagic (or type 2) cell death is characterized by the massive accumulation of autophagic vacuoles (autophagosomes) in the cytoplasm of cells that lack signs of apoptosis (type 1 cell death). Here we detail and critically assess a series of methods to promote and inhibit autophagy via pharmacological and genetic manipulations.