BAPTA-AM 细胞通透性螯合剂
BAPTA-AM 细胞通透性螯合剂
Invitrogen™

BAPTA-AM 细胞通透性螯合剂

BAPTA-AM 是一种细胞透性螯合剂,对 Ca2+ 的选择性超过 Mg2+,可以用于控制胞内 Ca2+ 水平。BAPTA 对 Ca2+了解更多信息
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货号数量
B676920 x 1mg
B120525mg
货号 B6769
价格(CNY)
5,157.00
Each
添加至购物车
数量:
20 x 1mg
价格(CNY)
5,157.00
Each
添加至购物车
BAPTA-AM 是一种细胞透性螯合剂,对 Ca2+ 的选择性超过 Mg2+,可以用于控制胞内 Ca2+ 水平。BAPTA 对 Ca2+ 的选择性强于 EDTA 和 EGTA,其金属螯合对 pH 相对更不敏感。
仅供科研使用。不可用于诊断程序。
规格
染料类型螯合物(非荧光)
数量20 x 1mg
运输条件室温
适用于(应用)细胞活力与增殖
产品类型细胞活力与增殖
Unit SizeEach
内容与储存
在冰箱中(-5°C 至 -30°C)储存。

引用和文献 (662)

引用和文献
Abstract
Rescue of vasopressin V2 receptor mutants by chemical chaperones: specificity and mechanism.
Authors:Robben JH,Sze M,Knoers NV,Deen PM
Journal:Molecular biology of the cell
PubMed ID:16267275
Because missense mutations in genetic diseases of membrane proteins often result in endoplasmic reticulum (ER) retention of functional proteins, drug-induced rescue of their cell surface expression and understanding the underlying mechanism are of clinical value. To study this, we tested chemical chaperones and sarco(endo)plasmic reticulum Ca(2+) ATPase pump inhibitors on ... More
The small GTP-binding protein Rac promotes the dissociation of gelsolin from actin filaments in neutrophils.
Authors:Arcaro A
Journal:J Biol Chem
PubMed ID:9422735
Gelsolin is an actin filament-capping protein that has been shown to play a key role in cell migration. Here we have studied the involvement of phosphoinositide 3-kinase (PI 3-kinase) and GTP-binding proteins (G-proteins) in the regulation of gelsolin-actin interactions in neutrophils. Inhibition of PI 3-kinase activity in vivo by wortmannin ... More
Isoform-specific up-regulation by ouabain of Na+,K+-ATPase in cultured rat astrocytes.
Authors:Hosoi R, Matsuda T, Asano S, Nakamura H, Hashimoto H, Takuma K, Baba A
Journal:J Neurochem
PubMed ID:9349566
There are two alpha-subunit isoforms (alpha1 and alpha2) and two beta-subunit isoforms (beta1 and beta2) of Na+,K+-ATPase in astrocytes, but the functional heterodimer composition is not known. Ouabain (0.5-1.0 mM) increased the levels of alpha1 and beta1 mRNAs, whereas it decreased those of alpha2 and beta2 mRNAs in cultured rat ... More
Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei.
Authors:Neamati N, Fernandez A, Wright S, Kiefer J, McConkey DJ
Journal:J Immunol
PubMed ID:7535814
Chromatin condensation and nuclear envelope breakdown are characteristic features of apoptotic cell death, but the mechanisms underlying these phenomena have not been identified. Solubilization of nuclear lamin is responsible for both events in mitosis. In this work, we report that glucocorticoids stimulate rapid degradation of lamin B1 that occurs before ... More
Calcineurin feedback inhibition of agonist-evoked cAMP formation.
Authors:Antoni FA, Barnard RJ, Shipston MJ, Smith SM, Simpson J, Paterson JM
Journal:J Biol Chem
PubMed ID:7499291
The effects of immunosuppressant blockers of calcineurin (protein phosphatase 2B) on cAMP formation and hormone release were investigated in mouse pituitary tumor (AtT20) cells. Immunosuppressants enhanced corticotropin-releasing factor- and isoproterenol-evoked cAMP production in proportion with their potency to block calcineurin. Further analysis of cAMP production revealed that intracellular Ca2+ derived ... More