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引用和文献 (33)
Invitrogen™
DiOC2(3)（3,3'-二乙基氧杂羰花青碘）
DiOC2(3) 是膜电位探针。其亦可用于通过流式细胞术，利用荧光发射比检测分析细菌活率。了解更多信息
| 货号 | 数量 |
|---|---|
| D14730 | 100 mg |
货号 D14730
价格（CNY)
3,543.00
Each
数量:
100 mg
价格（CNY)
3,543.00
Each
DiOC2(3) 是膜电位探针。其亦可用于通过流式细胞术，利用荧光发射比检测分析细菌活率。
仅供科研使用。不可用于诊断程序。
规格
检测方法荧光
数量100 mg
运输条件室温
子细胞定位细胞膜&脂质
颜色绿色
适用于（设备）荧光显微镜
产品类型DiOC2(3)
Unit SizeEach
内容与储存
室温避光储存。
常见问题解答 (FAQ)
当我使用膜电位指示剂时，看到神经元周围出现了较高的背景，如何降低背景干扰？
我用DiI一类的亲脂性花青染料进行细胞染色，但是当我试图继续用抗体标记时信号却丢失了。 这是什么原因所致？
快反应膜电位探针和慢反应膜电位探针有什么区别？
你们提供哪些类型的膜电位指示剂？我该如何根据自己的试验选择？
亲脂性示踪剂跨膜转运需要多久？FAST亲脂性染料能快多少？
引用和文献 (33)
引用和文献
Abstract
Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay.
Journal:Cytometry A
PubMed ID:12766968
'BACKGROUND: During transport-associated adenosine triphosphate hydrolysis, P-glycoprotein (Pgp) undergoes conformation transitions detected by UIC2, a functional anti-Pgp monoclonal antibody. A newly developed UIC2 shift assay is based on increased UIC2 reactivity in the presence of Pgp substrates. All peripheral blood leukocytes express low Pgp levels. The existing antibody-based detection methods
Fluorescent cationic probes of mitochondria. Metrics and mechanism of interaction.
Journal:Biophys J
PubMed ID:2605307
'Mitochondria strongly accumulate amphiphilic cations. We report here a study of the association of respiring rat liver mitochondria with several fluorescent cationic dyes from differing structural classes. Using gravimetric and fluorometric analysis of dye partition, we find that dyes and mitochondria interact in three ways: (a) uptake with fluorescence quenching,
The repetitive calcium waves in the fertilized ascidian egg are initiated near the vegetal pole by a cortical pacemaker.
Journal:Dev Biol
PubMed ID:1397683
'Ascidian eggs respond to fertilization with a series of repetitive calcium waves that originate mostly from the vegetal/contraction pole region (J. E. Speksnijder, C. Sardet, and L. F. Jaffe, 1990, Dev. Biol. 142, 246-249), where the myoplasm is concentrated during the first phase of ooplasmic segregation. This suggests that the
Transmembrane inhibitors of P-glycoprotein, an ABC transporter.
Journal:J Med Chem
PubMed ID:15916428
'Drug resistance mediated by ABC transporters such as P-glycoprotein (P-gp) continues to be a major impediment to effective cancer chemotherapy. We have developed a panel of highly specific peptide inhibitors of P-gp based on the structure of the transmembrane domains of the transporter. These peptides are thought to exert their
DiOC2(3) is not a substrate for multidrug resistance protein (MRP)-mediated drug efflux.
Journal:Cytometry
PubMed ID:8875050
'Multidrug resistance (MDR) is often related to expression of P-glycoprotein (Pgp) or Multidrug Resistance Protein (MRP). Pgp-mediated MDR can be evaluated by determining cellular retention of fluorescent substrates by flow cytometry. This study determined if agents used to evaluate Pgp function also can be used to evaluate MRP function. Cellular