Ultrathin self-assembled fibrin sheets.
Authors:O'Brien ET, Falvo MR, Millard D, Eastwood B, Taylor RM, Superfine R,
Journal:Proc Natl Acad Sci U S A
PubMed ID:19052234
'Fibrin polymerizes into the fibrous network that is the major structural component of blood clots and thrombi. We demonstrate that fibrin from three different species can also spontaneously polymerize into extensive, molecularly thin, 2D sheets. Sheet assembly occurs in physiologic buffers on both hydrophobic and hydrophilic surfaces, but is routinely ... More