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          • Home
          • › Search Tool
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          • › Mm00476361_m1
          See other NFKB1 GE Assays ›
          Gene Symbol:
          Nfkb1
          Gene Name:
          nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
          Gene Aliases:
          NF-KB1, NF-kappaB, NF-kappaB1, p105, p50, p50/p105
          Chromosome Location:
          Chr.3: 135584655 - 135691547 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00476361_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price
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          • Genomic Map
          • Assay Details
          • More Information
          • Citations (1)

          Genomic Map

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          Assay Details

          Gene Symbol: Nfkb1
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_008689.2 NP_032715.2 6 - 7 753 70
          GenBank mRNA AB119195.1 - 4 - 5 251 70
          AB221614.1 - 4 - 5 258 70
          AK052726.1 - 1 - 2 61 70
          AY423849.1 - 1 - 2 92 70
          AY521462.1 - 4 - 5 251 70
          AY521463.1 - 4 - 5 251 70
          BC050841.1 - 6 - 7 753 70
          BC138535.1 - 5 - 6 330 8861555 70
          BC138536.1 - 5 - 6 330 8861556 70
          M57999.1 - 6 - 7 542 70

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0300002994.mm.1

          Additional Information:

          This assay is in the 5'UTR region of the AK052726.1 transcripts.

          Set Membership:

          Ambion siRNA available Amplicon length less than or equal to 70 Apoptosis Mammalian Gene Collection Recommended Assay Mus musculus Mouse Chemokine Panel Mouse Estrogen Panel Mouse Immune Response 1700 Inventoried Mouse_Immune_Response Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Nfkb1

          Panther Classification:

          Molecular Function -

          Rel homology transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          negative regulation of cytokine production
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          apoptotic process
          inflammatory response
          response to oxidative stress
          signal transduction
          I-kappaB kinase/NF-kappaB signaling
          negative regulation of calcidiol 1-monooxygenase activity
          response to cytokine
          response to muscle stretch
          NIK/NF-kappaB signaling
          negative regulation of apoptotic process
          negative regulation of interleukin-12 biosynthetic process
          innate immune response
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          lymph node development
          negative regulation of inflammatory response
          cellular response to lipopolysaccharide
          cellular response to nicotine
          cellular response to interleukin-6
          cellular response to dsRNA
          cellular response to peptide hormone stimulus
          positive regulation of canonical Wnt signaling pathway
          positive regulation of hyaluronan biosynthetic process
          positive regulation of miRNA metabolic process
          regulatory region DNA binding
          transcription regulatory region sequence-specific DNA binding
          RNA polymerase II regulatory region sequence-specific DNA binding
          RNA polymerase II distal enhancer sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
          transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
          DNA binding
          chromatin binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          heat shock protein binding
          identical protein binding
          protein homodimerization activity
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          protein heterodimerization activity

          MicroArray Probes:

          Affymetrix ABI

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0300023642.mm.1 NM_008689.2.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0300023642.mm.1 NM_008689.2 Refseq
          Affymetrix Mouse Clariom S Array PSR0300023642.mm.1 TC0300002994.mm.1 MTA TC
          Array Name Probe IDs Targets Target Type
          ABI Mouse Genome Survey Microarray 914937 - -

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          Citations (1)

          Regulation of nuclear factor kappaB in the hippocampus by group I metabotropic glutamate receptors.
          Authors
          O'Riordan KJ, Huang IC, Pizzi M, Spano P, Boroni F, Egli R, Desai P, Fitch O, Malone L, Ahn HJ, Liou HC, Sweatt JD, Levenson JM
          Journal
          J Neurosci - Page No 4870 (Wed May 03 00:00:00 EDT 2006)
          Volume (Year)
          26 (2006)
          Product Usage
          -

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