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Gene Symbol:: CXCL10
Gene Name:: C-X-C motif chemokine ligand 10
Gene Aliases:: C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
Chromosome Location:: Chr.4: 76021116 - 76023536 on Build GRCh38
Species:: Human
Species Specific ID (Flybase ID):: -

Assay ID

Hs00171042_m1

Best Coverage

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Availability	Inventoried
Catalog #	4331182
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Genomic Map
Assay Details
More Information
Citations (17)

Assay Details

Gene Symbol: CXCL10
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001565.3	NP_001556.2	1 - 2	168		98
GenBank mRNA	BC010954.1	-	1 - 2	133	4274617	98
GenBank mRNA	X02530.1	-	1 - 2	129		98

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0400011053.hg.1
This assay targets the same location as HTA transcript cluster(s) TC04001305.hg.1

Set Membership:

Ambion siRNA available

Amplicon length between 86 and 100

Immune Tolerance Network

Mammalian Gene Collection

Recommended Assay

Homo sapiens

Human Chemokine Panel

Human Immune Response

Human Angiogenesis

Inventoried

Human_Immune

Human_Angiogenesis

Human_Chemokine

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene CXCL10

Panther Classification:

Molecular Function -

chemokine

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR04017887.hg.1	TC04001305.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR04017887.hg.1	ENST00000306602.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR04017887.hg.1	NM_001565.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	PSR0400175301.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0400175301.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	PSR0400175301.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0400175301.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	PSR0400175301.hg.1	TC0400011053.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	ENST00000306602.2	Ensembl
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	NM_001565.3	Refseq
Affymetrix Human Clariom D Assay	TC0400011053.hg.1	NM_001565.3	Refseq

Citations (17)

The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.

Authors: Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
Journal: Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 EDT 2009)
Volume (Year): 52 (2009)
Product Usage: -

Intrahepatic levels of CXCR3-associated chemokines correlate with liver inflammation and fibrosis in chronic hepatitis C.

Authors: Zeremski M, Petrovic LM, Chiriboga L, Brown QB, Yee HT, Kinkhabwala M, Jacobson IM, Dimova R, Markatou M, Talal AH
Journal: Hepatology - Page No 1440 (Sat Nov 01 00:00:00 EDT 2008)
Volume (Year): 48 (2008)
Product Usage: -

No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis.

Authors: Wiken M, Idali F, Al Hayja MA, Grunewald J, Eklund A, Wahlstrom J
Journal: Respir Res - Page No 121 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 11 (2010)
Product Usage: -

Gene expression profiles in psoriasis: analysis of impact of body site location and clinical severity.

Authors: Quekenborn-Trinquet V, Fogel P, Aldana-Jammayrac O, Ancian P, Demarchez M, Rossio P, Richards HL, Kirby B, Nguyen C, Voegel JJ, Griffiths CE
Journal: Br J Dermatol - Page No 489 (Tue Mar 01 00:00:00 EST 2005)
Volume (Year): 152 (2005)
Product Usage: -

Gene-expression analysis of polyI:C-stimulated primary human conjunctival epithelial cells.

Authors: Ueta M, Mizushima K, Yokoi N, Naito Y, Kinoshita S
Journal: Br J Ophthalmol - Page No 1528 (Mon Nov 01 00:00:00 EDT 2010)
Volume (Year): 94 (2010)
Product Usage: -

Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human monocyte-derived DCs.

Authors: Pietila TE, Latvala S, Osterlund P, Julkunen I
Journal: J Leukoc Biol - Page No 665 (Fri Oct 01 00:00:00 EDT 2010)
Volume (Year): 88 (2010)
Product Usage: -

Evaluation of CXCL9 and CXCL10 as circulating biomarkers of human cardiac allograft rejection.

Authors: Karason K, Jernas M, Hagg DA, Svensson PA
Journal: Bmc Cardiovasc Disord - Page No 29 (Sun Jan 01 00:00:00 EST 2006)
Volume (Year): 6 (2006)
Product Usage: -

Hepatitis C virus proteins interfere with the activation of chemokine gene promoters and downregulate chemokine gene expression.

Authors: Sillanpaa M, Kaukinen P, Melen K, Julkunen I
Journal: J Gen Virol - Page No 432 (Fri Feb 01 00:00:00 EST 2008)
Volume (Year): 89 (2008)
Product Usage: -

Identification of new sensitive biomarkers for the in vivo response to interferon-beta treatment in multiple sclerosis using DNA-array evaluation.

Authors: Sellebjerg F, Krakauer M, Hesse D, Ryder LP, Alsing I, Jensen PE, Koch-Henriksen N, Svejgaard A, Soelberg Sorensen P
Journal: Eur J Neurol - Page No 1291 (Tue Dec 01 00:00:00 EST 2009)
Volume (Year): 16 (2009)
Product Usage: -

15-Lipoxygenase-1 induces expression and release of chemokines in cultured human lung epithelial cells.

Authors: Liu C, Xu D, Liu L, Schain F, Brunnstrom A, Bjorkholm M, Claesson HE, Sjoberg J
Journal: Am J Physiol Lung Cell Mol Physiol - Page No L196 (Wed Jul 01 00:00:00 EDT 2009)
Volume (Year): 297 (2009)
Product Usage: -

STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines.

Authors: Fryknas M, Dhar S, Oberg F, Rickardson L, Rydaker M, Goransson H, Gustafsson M, Pettersson U, Nygren P, Larsson R, Isaksson A
Journal: Int J Cancer - Page No 189 (Mon Jan 01 00:00:00 EST 2007)
Volume (Year): 120 (2007)
Product Usage: -

Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients.

Authors: Decalf J, Fernandes S, Longman R, Ahloulay M, Audat F, Lefrerre F, Rice CM, Pol S, Albert ML
Journal: J Exp Med - Page No 2423 (Mon Oct 01 00:00:00 EDT 2007)
Volume (Year): 204 (2007)
Product Usage: -

Using distinct molecular signatures of human monocytes and dendritic cells to predict adjuvant activity and pyrogenicity of TLR agonists.

Authors: Kamgang RK, Ramos I, Rodrigues Duarte L, Ghielmetti M, Freudenberg M, Dahinden C, Padovan E
Journal: Med Microbiol Immunol - Page No 369 (Mon Dec 01 00:00:00 EST 2008)
Volume (Year): 197 (2008)
Product Usage: -

cDNA microarray analysis of serially sampled cervical cancer specimens from patients treated with thermochemoradiotherapy.

Authors: Borkamo ED, Schem BC, Fluge O, Bruland O, Dahl O, Mella O
Journal: Int J Radiat Oncol Biol Phys - Page No 1562 (Tue Dec 01 00:00:00 EST 2009)
Volume (Year): 75 (2009)
Product Usage: -

Adenovirus-directed ocular innate immunity: the role of conjunctival defensin-like chemokines (IP-10, I-TAC) and phagocytic human defensin-alpha.

Authors: Harvey SA, Romanowski EG, Yates KA, Gordon YJ
Journal: Invest Ophthalmol Vis Sci - Page No 3657 (Sat Oct 01 00:00:00 EDT 2005)
Volume (Year): 46 (2005)
Product Usage: -

Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.

Authors: Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM
Journal: Clin Exp Immunol - Page No 479 (Mon Jun 01 00:00:00 EDT 2009)
Volume (Year): 156 (2009)
Product Usage: -

Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment.

Authors: Harlin H, Meng Y, Peterson AC, Zha Y, Tretiakova M, Slingluff C, McKee M, Gajewski TF
Journal: Cancer Res - Page No 3077 (Wed Apr 01 00:00:00 EDT 2009)
Volume (Year): 69 (2009)
Product Usage: -