Antibodies that detect ADAM17 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target ADAM17 in Human, Mouse, Rat and Non-human primate samples. Our ADAM17 polyclonal,...Antibodies that detect ADAM17 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target ADAM17 in Human, Mouse, Rat and Non-human primate samples. Our ADAM17 polyclonal, monoclonal and recombinant monoclonal...Antibodies that detect ADAM17 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target ADAM17 in Human, Mouse, Rat and Non-human primate samples. Our ADAM17 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat, Alpaca and Chicken. These antibodies have been verified by Knockdown and Knockout to confirm specificity to ADAM17. Find the ADAM17 antibody that fits your needs. Choose from 1 of 26 ADAM17 antibodies, which have been validated in experiments with 15 publications and 76 images featured in our data gallery.
Browse primary antibodies for WB, Flow,...
Antibodies that detect ADAM17 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Flow Cytometry. These antibodies target ADAM17 in Human, Mouse, Rat and Non-human primate samples. Our ADAM17 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse, Goat, Alpaca and Chicken. These antibodies have been verified by Knockdown and Knockout to confirm specificity to ADAM17. Find the ADAM17 antibody that fits your needs. Choose from 1 of 26 ADAM17 antibodies, which have been validated in experiments with 15 publications and 76 images featured in our data gallery.
Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.
靶标信息
ADAM17 (disintegrin and metalloproteinase domain-containing protein 17) cleaves the membrane bound precusor of TNF-alpha to its mature soluble form. ADAM 17 is responsbile for the proteolytical release of soluble JAM3 from endothelial cells surface and the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1, and the amyloid precursor protein. It acts as an activator of the Notch pathway by mediating cleavage of Notch and generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Mutations in the gene can result in inflammatory skin and bowel disease, neonatal 1.
同义词
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme
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