Bub1 Antibodies

Antibodies that detect Bub1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Bub1 in Human, Mouse, Rat and Canine samples. Our Bub1 polyclonal, monoclonal and recombinant... Antibodies that detect Bub1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Bub1 in Human, Mouse, Rat and Canine samples. Our Bub1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in... Antibodies that detect Bub1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Bub1 in Human, Mouse, Rat and Canine samples. Our Bub1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the Bub1 antibody that fits your needs. Choose from 1 of 27 Bub1 antibodies, which have been validated in experiments with 8 publications and 57 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the... Antibodies that detect Bub1 can be used in several scientific applications, including Western Blot, Immunocytochemistry, ELISA, Immunohistochemistry and Flow Cytometry. These antibodies target Bub1 in Human, Mouse, Rat and Canine samples. Our Bub1 polyclonal, monoclonal and recombinant monoclonal antibodies are developed in Rabbit, Mouse and Goat. Find the Bub1 antibody that fits your needs. Choose from 1 of 27 Bub1 antibodies, which have been validated in experiments with 8 publications and 57 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

The BUB1 gene encodes a serine/threonine-protein kinase that is integral to the spindle assembly checkpoint, a crucial mechanism ensuring proper chromosome alignment and segregation during mitosis. BUB1 is involved in detecting and correcting errors in kinetochore-microtubule attachments, which is vital for maintaining genomic stability. It acts by delaying the onset of anaphase until all chromosomes are correctly attached to the spindle apparatus. BUB1 is recruited to kinetochores in early mitosis, where it phosphorylates several substrates to activate other checkpoint proteins, such as BUBR1 and MAD2, thereby preventing premature progression through mitosis. Mutations or aberrations in the expression levels of BUB1 are often associated with aneuploidy and chromosomal instability, contributing to cancer progression. BUB1 is thus considered a potential target for cancer therapeutics, aiming to exploit its role in the mitotic checkpoint to selectively eliminate tumor cells through checkpoint bypass or mitotic arrest.

同义词

Aamp; Aamp-rs; AL022991; angio associated migratory cell protein; angio-associated migratory cell protein; angio-associated migratory protein; angio-associated, migratory cell protein; AU040907; BUB1; BUB1 budding uninhibited by benzimidazoles 1 homolog; BUB1 mitotic checkpoint serine/threonine kinase; BUB1, mitotic checkpoint serine/threonine kinase; BUB1A; BUB1L; budding uninhibited by benzimidazoles 1 homolog; budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae); C80208; D2Xrf87; hBUB1; mBUB1; mitotic checkpoint serine/threonine-protein kinase BUB1; mitotic spindle checkpoint kinase; putative serine/threonine-protein kinase

Bub1 Antibodies

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