RAP1GAP Antibodies

Antibodies that detect RAP1GAP can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAP1GAP in Human, Mouse and Rat samples. Our RAP1GAP polyclonal, recombinant... Antibodies that detect RAP1GAP can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAP1GAP in Human, Mouse and Rat samples. Our RAP1GAP polyclonal, recombinant monoclonal and monoclonal antibodies are... Antibodies that detect RAP1GAP can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAP1GAP in Human, Mouse and Rat samples. Our RAP1GAP polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the RAP1GAP antibody that fits your needs. Choose from 1 of 18 RAP1GAP antibodies, which have been validated in experiments with 45 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen... Antibodies that detect RAP1GAP can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA and Flow Cytometry. These antibodies target RAP1GAP in Human, Mouse and Rat samples. Our RAP1GAP polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit and Mouse. Find the RAP1GAP antibody that fits your needs. Choose from 1 of 18 RAP1GAP antibodies, which have been validated in experiments with 45 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

Rap1GAP specifically stimulates GTP hydrolytic activity of the monomeric G protein Rap1. Physical interaction between G alpha z, a member of the Gi family of trimeric G proteins, and Rap1GAP blocks the ability of regulators of G protein signaling to stimulate GTP hydrolysis of the alpha subunit, and also attenuates the ability of activated G alpha z to inhibit adenylyl cyclase. Rap1GAP is expressed in the brain, kidney and pancreas and may act as a signal integrator to coordinate and/or integrate Gz signaling and Rap1 signaling in cells. A novel isoform of Rapl GTPase-activating protein, designated Rap1GAPII, binds specifically to G alpha z. Stimulation of the Gi-coupled M2 Muscarinic receptor translocates Rap1GAPII from the cytosol to the membrane and decreases the amount of GTP-bound Rap1, resulting in the activation of ERK/MAPK.

同义词

1300019I11Rik; 2310004O14Rik; AI427470; ARPP-90; KIAA0474; RAP1 GTPase activating protein; Rap1 GTPase-activating protein; rap1 GTPase-activating protein 1; Rap1, GTPase-activating protein 1; Rap1ga1; Rap1GAP; Rap1GAP1; RAP1GAPII; RAPGAP

RAP1GAP Antibodies

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