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Proteintech
DOCK8 Recombinant Rabbit Monoclonal Antibody (230441A2), CoraLite® Plus 488
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产品信息
CL488-83270-2
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
230441A2
抗原
DOCK8 fusion protein Ag34585
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1000 µg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: EVYKLVIPIL EAHREFRKLT LTHSKLQRAF DSIVNKDHKR MFGTYFRVGF FGSKFGDLDE QEFVYKEPAI TKLPEISHRL EAFYGQCFGA EFVEVIKDST PVDKTKLDPN KAYIQITFVE PYFDEYEMKD RVTYFEKNFN LRRFMYTTPF TLEGRPRGEL HEQYRRNTVL TTMHAFPYIK TRISVIQKEE FVLTPIEVAI EDMKKKTLQL AVAINQEPPD AKMLQMVLQG SVGATVNQGP LEVAQVFLAE IPADPKLYRH HNKLRLCFKE FIMRCGEAVE KNKRLITADQ REYQQELKKN YNKLKENLRP MIERKIPELY KPIFRVESQK RDSFHRSSFR KCETQLSQGS
靶标信息
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1200017A24Rik; Dedicator of cytokinesis protein 8; epididymis luminal protein 205
基因别名: DOCK8; HEL-205; MRD2; ZIR8
UniProt ID: (Human) Q8NF50
Entrez Gene ID: (Human) 81704
