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引用和文献 (7)
Thermo Scientific™
GMBS（N-γ-马来酰亚胺基丁酰-氧琥珀酰亚胺酯）
Thermo Scientific Pierce GMBS 是一种胺对巯基交联剂，含有 NHS 酯和马来酰亚胺反应性基团，位于短间隔臂（7.3 埃）的相对两端了解更多信息
| 货号 | 数量 |
|---|---|
| 22309 | 50 mg |
货号 22309
价格（CNY)
3,613.00
Each
数量:
50 mg
价格（CNY)
3,613.00
Each
Thermo Scientific Pierce GMBS 是一种胺对巯基交联剂，含有 NHS 酯和马来酰亚胺反应性基团，位于短间隔臂（7.3 埃）的相对两端。
GMBS 的特点：
•反应性基团：NHS 酯和马来酰亚胺
•可与以下基团发生反应：氨基和巯基
•脂肪族间隔系列的 C4 同系物包括 AMAS、BMPS、GMBS 和 EMCS
•NHS 酯末端在 pH 值 7-9 条件下与伯胺偶联，形成稳定酰胺键
•马来酰亚胺在 pH 值 6.5-7.5 条件下与 -SH 基团反应，形成稳定硫醚键
•不可裂解
•不溶于水（首先溶于 DMF 或 DMSO）；与 Sulfo-GMBS 具有可比性
•短脂肪族间隔引发免疫应答的可能性较低
产品参考：
交联剂应用指南 -- 检索本产品的最新参考文献
GMBS 的特点：
•反应性基团：NHS 酯和马来酰亚胺
•可与以下基团发生反应：氨基和巯基
•脂肪族间隔系列的 C4 同系物包括 AMAS、BMPS、GMBS 和 EMCS
•NHS 酯末端在 pH 值 7-9 条件下与伯胺偶联，形成稳定酰胺键
•马来酰亚胺在 pH 值 6.5-7.5 条件下与 -SH 基团反应，形成稳定硫醚键
•不可裂解
•不溶于水（首先溶于 DMF 或 DMSO）；与 Sulfo-GMBS 具有可比性
•短脂肪族间隔引发免疫应答的可能性较低
产品参考：
交联剂应用指南 -- 检索本产品的最新参考文献
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述GMBS
形式粉末
标记方法化学标记
分子量280.23
聚乙二醇化否
产品线Pierce
数量50 mg
反应一部分马来酰亚胺、NHS 酯
运输条件环境
溶解度DMF、DMSO
间隔臂长7.3 Å
水溶性否
化学反应性胺-巯基
可裂解否
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子短 (<10 Å)
Unit SizeEach
内容与储存
接收后，请在 4°C 下干燥储存。
常见问题解答 (FAQ)
Can you provide the shelf-life for GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)?
引用和文献 (7)
引用和文献
Abstract
Solid phase DNA amplification: characterisation of primer attachment and amplification mechanisms.
Journal:Nucleic Acids Res
PubMed ID:11024189
Different chemical methods used to attach oligonucleotides by their 5'-end on a glass surface were tested in the framework of solid phase PCR where surface-bound instead of freely-diffusing primers are used to amplify DNA. Each method was first evaluated for its capacity to provide a high surface coverage of oligonucleotides
Covalent attachment of synthetic DNA to self-assembled monolayer films.
Journal:Nucleic Acids Res
PubMed ID:8760890
'The covalent attachment of thiol-modified DNA oligomers; to self-assembled monolayer silane films on fused silica and oxidized silicon substrates is described. A heterobifunctional crosslinking molecule bearing both thiol- and amino-reactive moieties was used to tether a DNA oligomer (modified at its terminus with a thiol group) to an aminosilane film
Recognition of galactan components of pectin by galectin-3.
Journal:FASEB J
PubMed ID:18832596
It has been reported that modified forms of pectin possess anticancer activity. To account for this bioactivity, it has been proposed that fragments of pectin molecules can act by binding to and inhibiting the various roles of the mammalian protein galectin 3 (Gal3) in cancer progression and metastasis. Despite this
Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver.
Journal:Blood
PubMed ID:21427291
Aged or damaged RBCs are effectively removed from the blood circulation by Kupffer cells in the liver, but little is known regarding the mechanism of the clearance process. Here we show that stabilin-1 and stabilin-2 in hepatic sinusoidal endothelial cells (HSECs) are critical in effectively clearing damaged RBCs in mouse
Mapping specific adhesive interactions on living human intestinal epithelial cells with atomic force microscopy.
Journal:FASEB J
PubMed ID:18263697
Specific molecular-receptor interactions with gut epithelium cells are important in understanding bioactivity of food components and drugs, binding of commensal microflora, attachment and initiation of defense mechanisms against pathogenic bacteria and for development of targeted delivery systems to the gut. However, methods for probing such interactions are lacking. Methodology has