RAGE Antibodies

Antibodies that detect RAGE can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target RAGE in Human, Rat, Mouse, Porcine and Canine samples. Our RAGE polyclonal, monoclonal,... Antibodies that detect RAGE can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target RAGE in Human, Rat, Mouse, Porcine and Canine samples. Our RAGE polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal... Antibodies that detect RAGE can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target RAGE in Human, Rat, Mouse, Porcine and Canine samples. Our RAGE polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Humanized rat, Rat and Sheep. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to RAGE. Find the RAGE antibody that fits your needs. Choose from 1 of 38 RAGE antibodies, which have been validated in experiments with 69 publications and 103 images featured in our data gallery.

Browse primary antibodies for WB,... Antibodies that detect RAGE can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Flow Cytometry and Immunocytochemistry. These antibodies target RAGE in Human, Rat, Mouse, Porcine and Canine samples. Our RAGE polyclonal, monoclonal, recombinant monoclonal and recombinant superclonal antibodies are developed in Rabbit, Mouse, Humanized rat, Rat and Sheep. These antibodies have been verified by Relative expression and Cell treatment to confirm specificity to RAGE. Find the RAGE antibody that fits your needs. Choose from 1 of 38 RAGE antibodies, which have been validated in experiments with 69 publications and 103 images featured in our data gallery.

Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. Antibodies with Advanced Verification data have been validated for specificity to ensure that the antibody binds to the antigen stated. If you cannot find the antibody you’re looking for, contact us today to develop custom antibodies for specific targets, species and applications.

靶标信息

The Receptor for Advanced Glycation End-products (RAGE) is a gene located on human chromosome 6p21.3, encoding a transmembrane receptor belonging to the immunoglobulin superfamily. RAGE is expressed in various tissues, with significant levels in the lungs, and plays a crucial role in cellular signaling and inflammation. As a receptor, RAGE binds multiple ligands, including advanced glycation end-products (AGEs), amyloid-beta peptide, high mobility group box 1 (HMGB1), and S100/calgranulin proteins, facilitating diverse pathological processes like inflammation, cancer progression, and neurodegeneration. The interaction between RAGE and its ligands triggers intracellular signaling pathways such as NF-kB activation, leading to inflammatory responses and oxidative stress. In the context of chronic diseases like diabetes, Alzheimer's, and cardiovascular diseases, RAGE is a critical mediator, linking metabolic disturbance to cellular dysfunction. Therapeutic targeting of RAGE signaling is under investigation, aiming to mitigate its contribution to inflammatory and degenerative diseases.

同义词

advanced glycation end product receptor; advanced glycation end-product receptor; advanced glycation end-products receptor; advanced glycosylation end product-specific receptor; advanced glycosylation end product-specific receptor variant 2; advanced glycosylation end product-specific receptor variant 3; advanced glycosylation end product-specific receptor variant 4; advanced glycosylation end product-specific receptor variant 5; advanced glycosylation end-product specific receptor; Ager; MAPK/MAK/MRK overlapping kinase; MOK; MOK protein kinase; RAGE; RAGE isoform NtRAGE-delta; RAGE isoform sRAGE-delta; RAGE/AGER; RAGE1; RAGE-1; RAGE-4 ORF3; receptor for advanced glycation endproducts; receptor for advanced glycation end-products variant 20; receptor for advanced glycosylation end products; receptor of advanced glycosylation end products of proteins; immunoglobulin superfamily; MHC class II; MHC class III; renal cell carcinoma antigen; renal tumor antigen 1; SCARJ1; sRAGE; STK30

RAGE Antibodies

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