Product References
Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium-Induced Colitis.
Cellular and molecular gastroenterology and hepatology
Lee Y,Kim SH,Jeong H,Kim KH,Jeon D,Cho Y,Lee D,Nam KT
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Immunohistochemistry
Tue Aug 22 00:00:00 EDT 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo.
Molecular medicine reports
Huo J,Liu T,Li F,Song X,Hou X
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
JCI insight
Yun JH,Lee C,Liu T,Liu S,Kim EY,Xu S,Curtis JL,Pinello L,Bowler RP,Silverman EK,Hersh CP,Zhou X
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.
Developmental cell
Dege C,Fegan KH,Creamer JP,Berrien-Elliott MM,Luff SA,Kim D,Wagner JA,Kingsley PD,McGrath KE,Fehniger TA,Palis J,Sturgeon CM
11-1271 was used in Flow cytometry/Cell sorting to identify an extra-embryonic origin of potently cytotoxic NK cells, suggesting that ontogenic origin is a relevant factor in designing hPSC-derived adoptive immunotherapies.
Mon Apr 20 00:00:00 EDT 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation.
Nature
Wilkinson AC,Ishida R,Kikuchi M,Sudo K,Morita M,Crisostomo RV,Yamamoto R,Loh KM,Nakamura Y,Watanabe M,Nakauchi H,Yamazaki S
11-1271 was used in Flow cytometry/Cell sorting to identify polyvinyl alcohol as a functionally superior replacement for serum albumin that is compatible with good manufacturing practice.
Mon Jul 01 00:00:00 EDT 2019
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Nature immunology
Twohig JP,Cardus Figueras A,Andrews R,Wiede F,Cossins BC,Derrac Soria A,Lewis MJ,Townsend MJ,Millrine D,Li J,Hill DG,Uceda Fernandez J,Liu X,Szomolay B,Pepper CJ,Taylor PR,Pitzalis C,Tiganis T,Williams NM,Jones GW,Jones SA
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer.
The Journal of clinical investigation
Soukup AA,Zheng Y,Mehta C,Wu J,Liu P,Cao M,Hofmann I,Zhou Y,Zhang J,Johnson KD,Choi K,Keles S,Bresnick EH
11-1271 was used in Flow cytometry/Cell sorting to study the mechanisms underlying how GATA2 enhancer disease mutations impact hematopoiesis and pathology.
Fri Mar 01 00:00:00 EST 2019
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.
Haematologica
Zhang Z,Huang Z,Ong B,Sahu C,Zeng H,Ruan HB
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.
Cell reports
Magen A,Nie J,Ciucci T,Tamoutounour S,Zhao Y,Mehta M,Tran B,McGavern DB,Hannenhalli S,Bosselut R
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Tue Dec 03 00:00:00 EST 2019
Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells.
JCI insight
Huang A,Shinde PV,Huang J,Senff T,Xu HC,Margotta C,Häussinger D,Willnow TE,Zhang J,Pandyra AA,Timm J,Weggen S,Lang KS,Lang PA
11-1271 was used in Flow cytometry/Cell sorting to show that progranulin (PGRN) can reduce NK cell cytotoxicity through reduction of NK cell expansion, granzyme B transcription, and NK cell-mediated lysis of target cells.
Thu Sep 05 00:00:00 EDT 2019
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Immunity
Emgård J,Kammoun H,García-Cassani B,Chesné J,Parigi SM,Jacob JM,Cheng HW,Evren E,Das S,Czarnewski P,Sleiers N,Melo-Gonzalez F,Kvedaraite E,Svensson M,Scandella E,Hepworth MR,Huber S,Ludewig B,Peduto L,Villablanca EJ,Veiga-Fernandes H,Pereira JP,Flavell RA,Willinger T
11-1271 was used in Flow cytometry/Cell sorting to show that GPR183 promotes lymphoid organ development and indicate that oxysterol-GPR183-dependent positioning within tissues controls ILC3 activity and intestinal homeostasis.
Tue Jan 16 00:00:00 EST 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
11-1271 was used in Flow Cytometry to indicate that the VHL-HIF-glycolysis axis is essential for the late-stage maturation and function of ILC2s via targeting IL-33-ST2 pathway.
Tue Feb 20 00:00:00 EST 2018
Human leukemia mutations corrupt but do not abrogate GATA-2 function.
Proceedings of the National Academy of Sciences of the United States of America
Katsumura KR,Mehta C,Hewitt KJ,Soukup AA,Fraga de Andrade I,Ranheim EA,Johnson KD,Bresnick EH
11-1271 was used in Flow cytometry/Cell sorting to determine whether distinct mutations differentially impact GATA 2 mechanisms.
Tue Oct 23 00:00:00 EDT 2018
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.
International journal of molecular medicine
Luo B,Chen K,Feng Q,Xiao W,Ma D,Yang H,Zhang C
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Notch Signaling Facilitates In Vitro Generation of Cross-Presenting Classical Dendritic Cells.
Cell reports
Kirkling ME,Cytlak U,Lau CM,Lewis KL,Resteu A,Khodadadi-Jamayran A,Siebel CW,Salmon H,Merad M,Tsirigos A,Collin M,Bigley V,Reizis B
11-1271 was used in Flow cytometry/Cell sorting to examine the role of Notch signalling in the in vitro generation of classical dendritic cells.
Tue Jun 19 00:00:00 EDT 2018
General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation.
Journal of neuroimmunology
Keil M,Sonner JK,Lanz TV,Oezen I,Bunse T,Bittner S,Meyer HV,Meuth SG,Wick W,Platten M
11127182 was used in flow cytometry to investigate the role of general control non-derepressible 2 in resolving autoimmune neuroinflammation
Mon Aug 15 00:00:00 EDT 2016
A simple, accurate and universal method for quantification of PCR.
BMC biotechnology
Boulter N,Suarez FG,Schibeci S,Sunderland T,Tolhurst O,Hunter T,Hodge G,Handelsman D,Simanainen U,Hendriks E,Duggan K
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Wed Mar 09 00:00:00 EST 2016
The GIY-YIG Type Endonuclease Ankyrin Repeat and LEM Domain-Containing Protein 1 (ANKLE1) Is Dispensable for Mouse Hematopoiesis.
PloS one
Braun J,Meixner A,Brachner A,Foisner R
11-1271 was used in Flow cytometry/Cell sorting to test whether ANKLE1 may contribute to Holliday junction resolution during DNA repair in mice.
Fri Aug 12 00:00:00 EDT 2016
ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation.
eLife
Pearson C,Thornton EE,McKenzie B,Schaupp AL,Huskens N,Griseri T,West N,Tung S,Seddon BP,Uhlig HH,Powrie F
11-1271 was used in Flow cytometry/Cell sorting to investigate how a small population of innate lymphoid cells (ILCs) has large effects on immune homeostasis, showing that ILC3s produce GM-CSF to orchestrate acute intestinal inflammation.
Mon Jan 18 00:00:00 EST 2016
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Science advances
Johnson KD,Kong G,Gao X,Chang YI,Hewitt KJ,Sanalkumar R,Prathibha R,Ranheim EA,Dewey CN,Zhang J,Bresnick EH
11-1271 was used in Flow cytometry/Cell sorting to illustrate a paradigm in which cis-elements in a locus differentially control stem and progenitor cell transitions.
Tue Sep 01 00:00:00 EDT 2015
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Type I interferon signaling enhances CD8+ T cell effector function and differentiation during murine gammaherpesvirus 68 infection.
Journal of virology
Jennings RN,Grayson JM,Barton ES
11-1271 was used in Flow cytometry/Cell sorting to assess T cell responses in IFNAR1(-/-) mice after MHV68 infection.
Mon Dec 01 00:00:00 EST 2014
Autophagy is a critical regulator of memory CD8(+) T cell formation.
eLife
Puleston DJ,Zhang H,Powell TJ,Lipina E,Sims S,Panse I,Watson AS,Cerundolo V,Townsend AR,Klenerman P,Simon AK
11-1271 was used in Flow cytometry/Cell sorting to show that mice lacking the autophagy gene Atg7 in T cells failed to establish CD8(+) T cell memory to influenza and MCMV infection.
Tue Nov 11 00:00:00 EST 2014
Elongated TCR alpha chain CDR3 favors an altered CD4 cytokine profile.
BMC biology
Reynolds C,Chong D,Raynsford E,Quigley K,Kelly D,Llewellyn-Hughes J,Altmann D,Boyton R
11-1271 was used in Flow cytometry/Cell sorting to study how the conformation of TCR alpha chain CDR3 favours different CD4 cytokine profiles.
Fri May 09 00:00:00 EDT 2014
Uterine natural killer cells severely decrease in number at gestation day 6 in mice.
Biology of reproduction
Takashima A,Ishikawa F,Kuwabara T,Tanaka Y,Kinoshita T,Ito M,Kakiuchi T
11-1271 was used in Flow cytometry/Cell sorting to study how uterine NK cells or their precursors migrate into the uterus, mature, and produce interferon-gamma to support pregnancy in mice.
Tue Oct 01 00:00:00 EDT 2013
Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo.
PloS one
Wu X,Satpathy AT,Kc W,Liu P,Murphy TL,Murphy KM
11-1271 was used in Flow cytometry/Cell sorting to investigate the role of Bcl11a in the development of dendritic cells, showing that it controls Flt3 expression in early hematopoietic progenitors and is required for pDC development.
Fri Jan 10 00:00:00 EST 2014
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Nature medicine
Alvarez-Breckenridge CA,Yu J,Price R,Wojton J,Pradarelli J,Mao H,Wei M,Wang Y,He S,Hardcastle J,Fernandez SA,Kaur B,Lawler SE,Vivier E,Mandelboim O,Moretta A,Caligiuri MA,Chiocca EA
11-1271 was used in Flow cytometry/Cell sorting to demonstrate that glioblastoma virotherapy is limited partially by an antiviral NK cell response involving specific NCRs, uncovering new potential targets to enhance cancer virotherapy.
Sat Dec 01 00:00:00 EST 2012
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Nature immunology
Ochiai K,Maienschein-Cline M,Mandal M,Triggs JR,Bertolino E,Sciammas R,Dinner AR,Clark MR,Singh H
Published figure using CD127 monoclonal antibody (Product # 11-1271-82) in Flow Cytometry
Sun Jan 22 00:00:00 EST 2012
IFNγ induces monopoiesis and inhibits neutrophil development during inflammation.
Blood
de Bruin AM,Libregts SF,Valkhof M,Boon L,Touw IP,Nolte MA
11-1271 was used in Flow cytometry/Cell sorting to demonstrate that the pro-inflammatory cytokine IFNγ is involved in orchestrating inflammation-induced myelopoiesis.
Thu Feb 09 00:00:00 EST 2012
ZBTB1 is a determinant of lymphoid development.
The Journal of experimental medicine
Siggs OM,Li X,Xia Y,Beutler B
11-1271 was used in Flow cytometry/Cell sorting to identify a mutation causative of complete and cell-intrinsic T cell deficiency.
Mon Jan 16 00:00:00 EST 2012
Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors.
Neuro-oncology
Wainwright DA,Sengupta S,Han Y,Lesniak MS
11-1271 was used in Flow cytometry/Cell sorting to investigate whether brain-tumour-resident Tregs are thymus-derived natural Tregs or induced Tregs, showing that thymus-derived Tregs predominate.
Thu Dec 01 00:00:00 EST 2011
T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis.
PLoS pathogens
Bockstal V,Guirnalda P,Caljon G,Goenka R,Telfer JC,Frenkel D,Radwanska M,Magez S,Black SJ
11-1271 was used in Flow cytometry/Cell sorting to study how infection-induced deletion of transitional B cells prevents replenishment of mature B cell compartments during T. brucei infection.
Wed Jun 01 00:00:00 EDT 2011
Partial restoration of T-cell function in aged mice by in vitro blockade of the PD-1/ PD-L1 pathway.
Aging cell
Lages CS,Lewkowich I,Sproles A,Wills-Karp M,Chougnet C
11-1271 was used in Flow cytometry/Cell sorting to suggest that blockade of the PD-1/PD-L1 is not likely to be efficient at restoring exhausted T-cell responses in aged hosts.
Fri Oct 01 00:00:00 EDT 2010
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.
Journal of immunology (Baltimore, Md. : 1950)
Vondenhoff MF,Greuter M,Goverse G,Elewaut D,Dewint P,Ware CF,Hoorweg K,Kraal G,Mebius RE
Fri May 01 00:00:00 EDT 2009
Effector/memory but not naive regulatory T cells are responsible for the loss of concomitant tumor immunity.
Journal of immunology (Baltimore, Md. : 1950)
Lin YC,Chang LY,Huang CT,Peng HM,Dutta A,Chen TC,Yeh CT,Lin CY
11-1271 was used in Flow cytometry/Cell sorting to study the contribution of various Treg cell types to the maintenance of concomitant tumour immunity.
Fri May 15 00:00:00 EDT 2009
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
11-1271 was used in Flow cytometry/Cell sorting to show that the costimulatory molecule 4-1BB, and also its ligand 4-1BBL, is able to limit myelopoiesis and dendritic cell development.
Fri Aug 01 00:00:00 EDT 2008
IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.
Blood
Rubinstein MP,Lind NA,Purton JF,Filippou P,Best JA,McGhee PA,Surh CD,Goldrath AW
11-1271 was used in Flow cytometry/Cell sorting to study IL-7 and IL-15 regulation of CD8+ T-cell subsets during contraction of the immune response.
Sat Nov 01 00:00:00 EDT 2008
Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A.
Journal of virology
Sridhar S,Reyes-Sandoval A,Draper SJ,Moore AC,Gilbert SC,Gao GP,Wilson JM,Hill AV
11-1271 was used in Flow cytometry/Cell sorting to compare efficacy of AdH5 and AdC6 vector vaccines expressing antigen under HCMV promotion.
Tue Apr 01 00:00:00 EDT 2008
Unique receptor repertoire in mouse uterine NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Yadi H,Burke S,Madeja Z,Hemberger M,Moffett A,Colucci F
11-1271-82 was used in Flow Cytometry to define the receptor repertoire and phenotype of uterine NK cells at mid-gestation in mice.
Sat Nov 01 00:00:00 EDT 2008
Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis.
The American journal of pathology
Leithäuser F,Meinhardt-Krajina T,Fink K,Wotschke B,Möller P,Reimann J
Thu Jun 01 00:00:00 EDT 2006