Product References
XIAP promotes the expansion and limits the contraction of CD8 T cell response through cell extrinsic and intrinsic mechanisms respectively.
PLoS pathogens
Thakker P,Ariana A,Hajjar S,Cai D,Rijal D,Sad S
17-1271-82 was used in Flow cytometry/Cell sorting to reveal the temporal impact of XIAP in promoting the fitness of activated CD8 T cells through cell extrinsic and intrinsic mechanisms and provide a mechanistic explanation of the phenotype observed in XLP-2 patients.
Thu Jun 01 00:00:00 EDT 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells.
Cardiovascular research
Liu T,Meng Z,Liu J,Li J,Zhang Y,Deng Z,Luo S,Wang M,Huang Q,Zhang S,Fendt P,Devouassoux J,Li D,McKenzie ANJ,Nahrendorf M,Libby P,Guo J,Shi GP
17-1271-82 was used in Flow cytometry/Cell sorting to reveal an indirect cardiac reparative role of ILC2 in post-MI hearts via the IL5, EOS, and DC mechanism.
Tue May 02 00:00:00 EDT 2023
PRMT5 Deficiency Enforces the Transcriptional and Epigenetic Programs of Klrg1+CD8+ Terminal Effector T Cells and Promotes Cancer Development.
Journal of immunology (Baltimore, Md. : 1950)
Zheng Y,Chen Z,Zhou B,Chen S,Han L,Chen N,Ma Y,Xie G,Yang J,Nie H,Shen L
17-1271-82 was used in Flow cytometry/Cell sorting to validate the importance of targeting PRMT5 in tumor treatment, because PRMT5 deficiency enforced Klrg1+ terminal CD8+ T cell development and eliminated antitumor activity.
Sat Jan 15 00:00:00 EST 2022
Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.
Immunity
Denk D,Petrocelli V,Conche C,Drachsler M,Ziegler PK,Braun A,Kress A,Nicolas AM,Mohs K,Becker C,Neurath MF,Farin HF,Buchholz CJ,Andreux PA,Rinsch C,Greten FR
17-1271-82 was used in Sample Preparation to unravel a critical signaling pathway linking mitophagy to T memory stem cell formation and suggest that the metabolic compound Urolithin A represents an option to improve immune therapy.
Tue Nov 08 00:00:00 EST 2022
Organoids capture tissue-specific innate lymphoid cell development in mice and humans.
Cell reports
Jowett GM,Read E,Roberts LB,Coman D,Vilà González M,Zabinski T,Niazi U,Reis R,Trieu TJ,Danovi D,Gentleman E,Vallier L,Curtis MA,Lord GM,Neves JF
17-1271-82 was used in Flow cytometry/Cell sorting to demonstrate that human epithelial cells recapitulate maturation of ILC from a stringent systemic human ILCP population, but only when the organoid-associated stromal cells are depleted.
Tue Aug 30 00:00:00 EDT 2022
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo.
Molecular medicine reports
Huo J,Liu T,Li F,Song X,Hou X
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
JCI insight
Yun JH,Lee C,Liu T,Liu S,Kim EY,Xu S,Curtis JL,Pinello L,Bowler RP,Silverman EK,Hersh CP,Zhou X
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
Potently Cytotoxic Natural Killer Cells Initially Emerge from Erythro-Myeloid Progenitors during Mammalian Development.
Developmental cell
Dege C,Fegan KH,Creamer JP,Berrien-Elliott MM,Luff SA,Kim D,Wagner JA,Kingsley PD,McGrath KE,Fehniger TA,Palis J,Sturgeon CM
17-1271 was used in Flow cytometry/Cell sorting to identify an extra-embryonic origin of potently cytotoxic NK cells, suggesting that ontogenic origin is a relevant factor in designing hPSC-derived adoptive immunotherapies.
Mon Apr 20 00:00:00 EDT 2020
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.
Cell reports
Flosbach M,Oberle SG,Scherer S,Zecha J,von Hoesslin M,Wiede F,Chennupati V,Cullen JG,List M,Pauling JK,Baumbach J,Kuster B,Tiganis T,Zehn D
17-1271 was used in Flow cytometry/Cell sorting to show the therapeutic potential of targeting PTPN2 in T cell-based therapies to augment the number and survival capacity of antigen-specific T cells.
Tue Jul 28 00:00:00 EDT 2020
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Nature immunology
Twohig JP,Cardus Figueras A,Andrews R,Wiede F,Cossins BC,Derrac Soria A,Lewis MJ,Townsend MJ,Millrine D,Li J,Hill DG,Uceda Fernandez J,Liu X,Szomolay B,Pepper CJ,Taylor PR,Pitzalis C,Tiganis T,Williams NM,Jones GW,Jones SA
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.
Haematologica
Zhang Z,Huang Z,Ong B,Sahu C,Zeng H,Ruan HB
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.
Cell reports
Magen A,Nie J,Ciucci T,Tamoutounour S,Zhao Y,Mehta M,Tran B,McGavern DB,Hannenhalli S,Bosselut R
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Tue Dec 03 00:00:00 EST 2019
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.
Nature communications
Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O
17-1271-82 was used in Flow Cytometry to show that GITR, a member of the TNF superfamily, is expressed on both murine and human Type-2 innate lymphoid cells.
Tue Feb 12 00:00:00 EST 2019
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.
International journal of molecular medicine
Luo B,Chen K,Feng Q,Xiao W,Ma D,Yang H,Zhang C
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Runx-dependent and silencer-independent repression of a maturation enhancer in the Cd4 gene.
Nature communications
Kojo S,Yasmin N,Muroi S,Tenno M,Taniuchi I
17-1271 was used in Flow cytometry/Cell sorting to identify a late-acting maturation enhancer which plays essential roles for activation of both the early-acting proximal enhancer and maturation enhancer of Cd4.
Wed Sep 05 00:00:00 EDT 2018
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Nature medicine
Fenouille N,Bassil CF,Ben-Sahra I,Benajiba L,Alexe G,Ramos A,Pikman Y,Conway AS,Burgess MR,Li Q,Luciano F,Auberger P,Galinsky I,DeAngelo DJ,Stone RM,Zhang Y,Perkins AS,Shannon K,Hemann MT,Puissant A,Stegmaier K
17-1271 was used in Flow cytometry/Cell sorting to investigate the effect of MECOM on cellular metabolism.
Wed Mar 01 00:00:00 EST 2017
Culling of APCs by inflammatory cell death pathways restricts TIM3 and PD-1 expression and promotes the survival of primed CD8 T cells.
Cell death and differentiation
Patel R,Kim K,Shutinoski B,Wachholz K,Krishnan L,Sad S
17-1271 was used in Flow cytometry/Cell sorting to evaluate the impact of premature cell death of antigen-presenting cells by Caspase-1- and RipK3-signalling pathways on CD8+ T-cell priming during infection of mice with Salmonella typhimurium.
Wed Nov 01 00:00:00 EDT 2017
Bacillus anthracis lethal toxin negatively modulates ILC3 function through perturbation of IL-23-mediated MAPK signaling.
PLoS pathogens
Seshadri S,Allan DSJ,Carlyle JR,Zenewicz LA
17-1271 was used in Flow cytometry/Cell sorting to study the effects of MAPK signalling pathways in group 3 innate immune lymphocytes using Bacillus anthracis.
Sun Oct 01 00:00:00 EDT 2017
Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 iCreTbx21 fl/fl mice.
Wellcome open research
Cuff AO,Male V
17-1271 was used in Flow cytometry/Cell sorting to examine the role of Tbet-dependent type I innate lymphoid cells in the murine liver.
Sat Jan 09 00:00:00 EST 2021
IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.
JCI insight
Le Saout C,Luckey MA,Villarino AV,Smith M,Hasley RB,Myers TG,Imamichi H,Park JH,O'Shea JJ,Lane HC,Catalfamo M
17-1271 was used in Flow cytometry/Cell sorting to propose a model in which T cells undergoing lymphopenia-induced proliferation upregulate STAT1 protein, switching on an alternate IL-7-dependent program.
Thu Nov 16 00:00:00 EST 2017
A simple, accurate and universal method for quantification of PCR.
BMC biotechnology
Boulter N,Suarez FG,Schibeci S,Sunderland T,Tolhurst O,Hunter T,Hodge G,Handelsman D,Simanainen U,Hendriks E,Duggan K
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Wed Mar 09 00:00:00 EST 2016
Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.
Nature medicine
Yoda A,Adelmant G,Tamburini J,Chapuy B,Shindoh N,Yoda Y,Weigert O,Kopp N,Wu SC,Kim SS,Liu H,Tivey T,Christie AL,Elpek KG,Card J,Gritsman K,Gotlib J,Deininger MW,Makishima H,Turley SJ,Javidi-Sharifi N,Maciejewski JP,Jaiswal S,Ebert BL,Rodig SJ,Tyner JW,Marto JA,Weinstock DM,Lane AA
17127182 was used in flow cytometry to investigate the role of GNB1 and GNB2 in cancer cells.
Thu Jan 01 00:00:00 EST 2015
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia.
Genome medicine
Sonnet M,Claus R,Becker N,Zucknick M,Petersen J,Lipka DB,Oakes CC,Andrulis M,Lier A,Milsom MD,Witte T,Gu L,Kim-Wanner SZ,Schirmacher P,Wulfert M,Gattermann N,Lübbert M,Rosenbauer F,Rehli M,Bullinger L,Weichenhan D,Plass C
17-1271 was used in Flow cytometry/Cell sorting to investigate the onset of aberrant DNA methylation events and their dynamics during leukemic progression.
Thu Jun 19 00:00:00 EDT 2014
Kinetic and phenotypic analysis of CD8+ T cell responses after priming with alphavirus replicons and homologous or heterologous booster immunizations.
Journal of virology
Knudsen ML,Ljungberg K,Kakoulidou M,Kostic L,Hallengärd D,García-Arriaza J,Merits A,Esteban M,Liljeström P
17-1271 was used in Flow cytometry/Cell sorting to study CD8(+) T cell immune responses induced in mice after priming and boosting immunisations with nonproductive alphavirus replicons.
Sat Nov 01 00:00:00 EDT 2014
Pegylated bisacycloxypropylcysteine, a diacylated lipopeptide ligand of TLR6, plays a host-protective role against experimental Leishmania major infection.
Journal of immunology (Baltimore, Md. : 1950)
Pandey SP,Chandel HS,Srivastava S,Selvaraj S,Jha MK,Shukla D,Ebensen T,Guzman CA,Saha B
17-1271 was used in Flow cytometry/Cell sorting to investigate the functional differences in different TLR heterodimers.
Wed Oct 01 00:00:00 EDT 2014
Topical CpG adjuvantation of a protein-based vaccine induces protective immunity to Listeria monocytogenes.
Clinical and vaccine immunology : CVI
Cheng WK,Wee K,Kollmann TR,Dutz JP
17-1271 was used in Flow cytometry/Cell sorting to demonstrate that single topical administration of CpG ODN during parenteral immunisation may be used to induce protective immunity against L. monocytogenes.
Sat Mar 01 00:00:00 EST 2014
Variability of inducible expression across the hematopoietic system of tetracycline transactivator transgenic mice.
PloS one
Takiguchi M,Dow LE,Prier JE,Carmichael CL,Kile BT,Turner SJ,Lowe SW,Huang DC,Dickins RA
17-1271 was used in Flow cytometry/Cell sorting to characterise inducible gene/shRNA expression across a range of hematopoietic cell types of several commonly used transgenic tet transactivator mouse strains.
Fri Jul 19 00:00:00 EDT 2013
Thymic stromal lymphopoietin induces corticosteroid resistance in natural helper cells during airway inflammation.
Nature communications
Kabata H,Moro K,Fukunaga K,Suzuki Y,Miyata J,Masaki K,Betsuyaku T,Koyasu S,Asano K
17-1271 was used in Flow cytometry/Cell sorting to investigate the role of the IL-33/NH-cell axis in corticosteroid resistance.
Thu Jun 12 00:00:00 EDT 2014
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Nature immunology
Ochiai K,Maienschein-Cline M,Mandal M,Triggs JR,Bertolino E,Sciammas R,Dinner AR,Clark MR,Singh H
Published figure using CD127 monoclonal antibody (Product # 17-1271-82) in Flow Cytometry
Sun Jan 22 00:00:00 EST 2012
Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells.
The Journal of experimental medicine
Cherrier M,Sawa S,Eberl G
17-1271 was used in Flow cytometry/Cell sorting to investigate the development of lymphoid tissue inducer (LTi) cells from common lymphoid progenitors (CLPs) in the fetal liver, showing that sequential changes in expression of Notch, Id2, and RORγt orchestrate the development of LTi cells.
Mon Apr 09 00:00:00 EDT 2012
IL-33 induces innate lymphoid cell-mediated airway inflammation by activating mammalian target of rapamycin.
The Journal of allergy and clinical immunology
Salmond RJ,Mirchandani AS,Besnard AG,Bain CC,Thomson NC,Liew FY
17-1271 was used in Flow cytometry/Cell sorting to investigate the role of mTOR signalling in the activation of TH2, ILC and IL-33 inflammation responses.
Thu Nov 01 00:00:00 EDT 2012
Optimal isolation of functional Foxp3+ induced regulatory T cells using DEREG mice.
PloS one
Baru AM,Untucht C,Ganesh V,Hesse C,Mayer CT,Sparwasser T
17-1271 was used in Flow cytometry/Cell sorting to define culture conditions for efficient generation of eGFP(+)Foxp3(+) iTregs by use of DEREG mice.
Thu Feb 14 00:00:00 EST 2013
Autoimmune melanocyte destruction is required for robust CD8+ memory T cell responses to mouse melanoma.
The Journal of clinical investigation
Byrne KT,Côté AL,Zhang P,Steinberg SM,Guo Y,Allie R,Zhang W,Ernstoff MS,Usherwood EJ,Turk MJ
17-1271 was used in Flow cytometry/Cell sorting to show that vitiligo generates self antigen required for mounting persistent and protective memory CD8+ T cell responses to melanoma.
Sun May 01 00:00:00 EDT 2011
IL-7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo.
European journal of immunology
Pearson C,Silva A,Saini M,Seddon B
17-1271 was used in Flow cytometry/Cell sorting to study the molecular mechanisms by which IL-7 regulates the homeostatic fitness of T cells.
Thu Dec 01 00:00:00 EST 2011
Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization.
Journal of immunology (Baltimore, Md. : 1950)
Schmidt NW,Harty JT
17-1271 was used in Flow cytometry/Cell sorting to investigate whether unrelated infections will compromise numbers of Plasmodium-specific memory CD8 T cells, showing that attrition of Plasmodium-specific cells is rescued by booster immunisation.
Fri Apr 01 00:00:00 EDT 2011
Anti-gamma interferon antibodies enhance the immunogenicity of recombinant adenovirus vectors.
Clinical and vaccine immunology : CVI
Jackson SS,Schmitz JE,Letvin NL
17-1271 was used in Flow cytometry/Cell sorting to demonstrate the utility of anti-IFN-γ Ab for potentiating rAd immunizations to effect changes in effector and memory CTL populations.
Tue Nov 01 00:00:00 EDT 2011
One naive T cell, multiple fates in CD8+ T cell differentiation.
The Journal of experimental medicine
Gerlach C,van Heijst JW,Swart E,Sie D,Armstrong N,Kerkhoven RM,Zehn D,Bevan MJ,Schepers K,Schumacher TN
17-1271 was used in Flow cytometry/Cell sorting to assess the potential for development of single naive T cells into different subsets.
Mon Jun 07 00:00:00 EDT 2010
CD40 expression levels modulate regulatory T cells in Leishmania donovani infection.
Journal of immunology (Baltimore, Md. : 1950)
Martin S,Agarwal R,Murugaiyan G,Saha B
17-1271 was used in Flow cytometry/Cell sorting to investigate the role of dendritic cell-expressed CD40 in the generation of Tregs.
Thu Jul 01 00:00:00 EDT 2010
IL-7 adjuvant treatment enhances long-term tumor-antigen-specific CD8+ T-cell responses after immunization with recombinant lentivector.
Blood
Colombetti S,Lévy F,Chapatte L
17-1271 was used in Flow cytometry/Cell sorting to identify that IL-7 treatment should be beneficial in vaccinations settings in which high frequencies of effector CD8+ T cells do not down-regulate IL-7R expression upon priming, such as recombinant lentivector-based vaccines.
Thu Jun 25 00:00:00 EDT 2009
High frequencies of virus-specific CD8+ T-cell precursors.
Journal of virology
Seedhom MO,Jellison ER,Daniels KA,Welsh RM
17-1271 was used in Flow cytometry/Cell sorting to examine CD8(+) T-cell precursor frequencies for whole viruses.
Tue Dec 01 00:00:00 EST 2009
Reevaluating the CD8 T-cell response to herpes simplex virus type 1: involvement of CD8 T cells reactive to subdominant epitopes.
Journal of virology
Sheridan BS,Cherpes TL,Urban J,Kalinski P,Hendricks RL
17-1271 was used in Flow cytometry/Cell sorting to explore the properties of glycoprotein B-nonspecific trigeminal ganglia-resident CD8 T-cells and their role in maintaining viral latency.
Sun Mar 01 00:00:00 EST 2009
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.
Journal of immunology (Baltimore, Md. : 1950)
Vondenhoff MF,Greuter M,Goverse G,Elewaut D,Dewint P,Ware CF,Hoorweg K,Kraal G,Mebius RE
Fri May 01 00:00:00 EDT 2009
T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Smith E,von Vietinghoff S,Stark MA,Zarbock A,Sanders JM,Duley A,Rivera-Nieves J,Bender TP,Ley K
17-1271 was used in Flow cytometry/Cell sorting to investigate the requirement of the thymus and VDJ recombination in T cell lineages.
Sun Nov 01 00:00:00 EDT 2009
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.
Nature immunology
Lee SW,Park Y,So T,Kwon BS,Cheroutre H,Mittler RS,Croft M
17-1271 was used in Flow cytometry/Cell sorting to show that the costimulatory molecule 4-1BB, and also its ligand 4-1BBL, is able to limit myelopoiesis and dendritic cell development.
Fri Aug 01 00:00:00 EDT 2008
TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis.
The Journal of clinical investigation
Wang H,Peters T,Sindrilaru A,Kess D,Oreshkova T,Yu XZ,Seier AM,Schreiber H,Wlaschek M,Blakytny R,Röhrbein J,Schulz G,Weiss JM,Scharffetter-Kochanek K
17-1271 was used in Flow cytometry/Cell sorting to investigate the role of Tregs in the pathogenesis of psoriasis, showing that the TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18.
Tue Jul 01 00:00:00 EDT 2008
TRAIL deficiency does not rescue impaired CD8+ T cell memory generated in the absence of CD4+ T cell help.
Journal of immunology (Baltimore, Md. : 1950)
Sacks JA,Bevan MJ
17-1271 was used in Flow cytometry/Cell sorting to investigate the role of the proapoptotic molecule TRAIL in unhelped CD8(+) T cells.
Tue Apr 01 00:00:00 EDT 2008
Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis.
The American journal of pathology
Leithäuser F,Meinhardt-Krajina T,Fink K,Wotschke B,Möller P,Reimann J
Thu Jun 01 00:00:00 EDT 2006
