Search
A direct route to complete oncology research biomarker results in as little as 24 hours.
When turnaround times define how your lab performs, speed must be measured across the entire workflow—not just individual steps. Oncomine Assays on the Ion Torrent Genexus System enable end-to-end rapid next-generation sequencing (NGS) with an automated sample-to-result workflow, integrated analysis, just two user touchpoints, and minimal hands-on time. From targeted solid tumor genomic profiling in as little as 24 hours to next-day comprehensive genomic profiling and streamlined myeloid profiling, the portfolio is designed to help laboratories move faster with confidence.
End-to-end automated NGS workflow for rapid results
Some solutions emphasize speed in only one part of the workflow, such as library preparation or sequencing. But one fast step is not the same as a fast route to report. Delivering rapid results requires the entire sample-to-report workflow to move efficiently—from nucleic acid extraction and quantification through library preparation, sequencing, analysis, and reporting.
Oncomine Assays on the Ion Torrent Genexus System are designed to keep every step on track with an automated sample-to-result workflow run within one integrated software environment. With just two user touchpoints, minimal hands-on time, and simplified operation, laboratories can accelerate reporting while reducing operational complexity—even when resources are limited or prior NGS experience is minimal.
End-to-end automation
From nucleic acid extraction and quantification through library preparation, sequencing, analysis, and report generation.
Fast
turnaround
Targeted profiling can deliver results in as little as 24 hours, while comprehensive genomic profiling can be delivered as fast as next day.
Minimal
hands-on-time
Two user touchpoints and as little as 20 minutes hands-on time in key workflows.
One-vendor
simplicity
Instruments, consumables, analysis, and support from a single source.
The Ion Torrent Genexus System is designed to integrate key workflow steps within one software environment, helping laboratories move from nucleic acid extraction and quantification through library preparation, sequencing, analysis, and reporting with minimal hands-on time.
Figure: Ion Torrent Genexus System NGS automated workflow.
Compare the Oncomine NGS assay menu
Oncomine Assays on the Ion Torrent Genexus System offer a flexible route for clinical oncology research—from deep analysis of one key gene to targeted panels, comprehensive genomic profiling for solid tumors, and hematology research applications. Whether the priority is rapid, cost-efficient profiling of key solid tumor biomarkers, broad genomic insight, or streamlined myeloid profiling in hemato-oncology research, the portfolio is designed to combine speed, automation, and relevant biomarker coverage in one end-to-end workflow.
| Research area | One gene specific | Targeted panel | Expanded targeted panel | Comprehensive panel | Hematology |
| Assay | Oncomine BRCA Assay GX | Oncomine Precision Assay | Oncomine Comprehensive Assay v3 | Oncomine Comprehensive Assay Plus | Oncomine Myeloid Assay GX v2 |
| Description | Focused BRCA1/2 profiling | Rapid profiling of key solid tumor biomarkers | Broader biomarker coverage | Broad molecular profiling | Myeloid disorders profiling |
| Sample types | FFPE tissue, whole blood | FFPE tissue; liquid biopsy | FFPE tissue | FFPE tissue | Whole blood, peripheral blood leukocytes, bone marrow |
| Coverage | BRCA1/2 | 50 key genes, DNA and RNA | 161 genes, DNA and RNA | 517 genes, DNA and RNA | 45 DNA target genes and 34 RNA fusion driver genes |
| Alteration types | SNVs, indels, and large genomic rearrangements | SNVs, indels, CNVs, and fusions | DNA- and RNA-based biomarkers | SNVs, indels, CNVs, fusions, plus HRD, TMB, and MSI | SNVs, insertions, deletions, ITDs, PTDs, and gene fusions |
| Input | 10 ng DNA | 10 ng DNA or RNA | 10 ng DNA or RNA | 30 ng DNA / 20 ng RNA | 20 ng DNA / 10 ng RNA |
| Turnaround | As little as 24 hours | As little as 24 hours | As little as 24 hours | As fast as next day | As little as 24 hours |
Featured solutions for rapid oncology research profiling
These featured solutions highlight three distinct routes within the Oncomine portfolio: targeted profiling of solid tumor samples, next-day comprehensive genomic profiling, and streamlined myeloid profiling in hemato-oncology. Together, they show how laboratories can match assay depth to research need while staying within the same rapid, automated Genexus workflow.
Custom NGS solutions
If you do not see an Oncomine assay or panel that fits your needs, custom Ion AmpliSeq panels can help support projects ranging from a few regions to hundreds of targets. Create your own designs using the Ion AmpliSeq Designer online tool. This free online tool makes it easy to design customized AmpliSeq panels to meet your unique targeted NGS testing needs. Simply sign in and design your custom targeted NGS panel in minutes - no prior sequencing experience needed.
Service and support
Thermo Fisher Scientific supports Oncomine Solutions users with services designed to help laboratories implement, optimize, and sustain rapid NGS workflows with confidence. Whether you are a new customer in need of instrument setup assistance, an established user looking to troubleshoot, add a new assay to your workflow, or perform an analytical validation, support is available across the journey.
Oncomine support includes:
Customer concierge services
A single point of contact to help coordinate readiness, delivery, installation, and training scheduling.
Analytical validation consultation
Guidance for RUO workflow implementation, including project management consultation, workflow training, optimization, and technical review consultation.
Comprehensive instrument service and support
ISO-certified field engineers, qualification services, maintenance, and remote support.
Oncology application consultants
Support from extraction to report, including application training, troubleshooting, and quality control support.
Bioinformatics experts
Setup, maintenance, software upgrades, data backup, and training for bioinformatics solutions.
Order Oncomine Assays on the Genexus System
Frequently asked questions
Rapid next-generation sequencing (NGS) refers to workflows that significantly reduce the time from sample to result—often delivering genomic insights within the next day. It integrates automated sample preparation, sequencing, and data analysis to accelerate oncology research.
End-to-end rapid NGS on the Genexus System means a fully automated workflow that takes you from biological sample to analyzed results with minimal hands-on time as fast as in 24 hours.
Oncomine Assays on the Genexus System can deliver results in as little as 24 hours, depending on the assay type and workflow configuration.
The Oncomine Comprehensive Assay v3 GX, Oncomine BRCA Assay GX and Oncomine Precision Assay GX are designed for solid tumor genomic profiling.
The Oncomine Comprehensive Assay Plus supports broad genomic profiling, covering a wide range of DNA and RNA biomarkers for deeper tumor characterization.
The Oncomine Myeloid Assay GX v2 is designed specifically for profiling myeloid malignancies, enabling detection of relevant mutations, fusions, and gene expression markers.
Yes. The Genexus workflow is designed for ease of use, with automation and pre-optimized protocols that reduce manual steps and training requirements, making it accessible for labs with limited NGS experience.
Yes. Custom NGS solutions are available, allowing laboratories to tailor panels or workflows based on specific clinical research needs. Thermo Fisher Scientific offers custom Ion AmpliSeq panels to help support projects ranging from a few regions to hundreds of targets.
Ready to speak to a Thermo Fisher Scientific representative?
We will be happy to answer your questions and provide a demo of our NGS solutions.
For Research Use Only. Not for use in diagnostic procedures.
PMR-005753