Advanced technologies for cosmetic testing and personal care product development

Analysis and testing are crucial for verifying the efficacy of products, helping to make sure they deliver the promised textures, colors, flow, and benefits as well as maintain stability over time. Our technologies and instruments help support innovation, improve existing formulation, protect consumers, meet legal standards, and foster confidence in the products' safety and effectiveness.


Checkweighing

Weighing, counting, analysis, and process control technologies are used in checkweighing systems. A checkweigher weighs and counts products in motion and rejects products that do not meet pre-determined specifications. As a package moves onto the checkweigher infeed, it is weighed using a weigh cell in the weigh table. The package then moves onto the outfeed of the checkweigher to be accepted or rejected according to the checkweigher settings.  If a problem is indicated, a product is rejected and removed from the conveyor via an air blast, bopper, or pusher. The rejected products can also be diverted or dropped into a separate area for further inspection.

 

 Advances in these systems deliver reliable accuracy in weighing variable package sizes, without stopping or recalibrating the checkweigher conveyor. 

Global VersaWeigh Checkweigher

Thermo Scientific Global VersaWeigh Checkweighers feature frames designed to reduce material buildup, rapid-release, adjustable conveyors and belts, and high-torque sealed brushless motors for trouble-free operation. The fixed-height Global VersaWeigh Checkweigher is ideal for products up to 10 kilograms (22 pounds). 

Versa Flex Checkweighers

The Thermo Scientific Versa Flex Checkweighers are ideal for weighing a wide range of packaged cosmetic and personal care products in dry applications. From light to heavy-weight packages, both the Versa Flex (fixed height) and Versa Flex GP (height-adjustable cantilever) Checkweighers improve accuracy and reliability while decreasing product giveaway.

Global Versa GP Checkweigher

The Thermo Scientific Global Versa GP Checkweigher is a versatile, general purpose checkweigher that scans at line speeds up to 350 packages per minute without sacrificing accuracy. It comes with a compact cantilever construction for height adjustment and is ideal for packages up to 3 kilograms (6.6 pounds).

Versa Chain Checkweigher

The Thermo Scientific Versa Chain Checkweigher boasts line speeds up to 700 packages per minute. It provides reliable high-speed weighing, control, and reject functions for cartons, cans, bottles, and pouches in dry or wet environments.

Versa Rx Checkweigher for Pharmaceutical Applications

The Thermo Scientific Versa Rx Checkweigher, originally designed for the pharmaceutical industry, is of value to any application requiring highly accurate, high-rate weighing of light-weight products in a dry environment, such as small pouches of supplements or gummies. All components, including the weighing mechanism, electronics, and pneumatics for the reject device, are housed in a sanitary enclosure ideally suited for today’s ‘clean room’ environments.

Versa Flex Frame 44HD (Heavy Duty) Checkweigher

The Thermo Scientific Versa Flex Frame 44HD Checkweigher offers dependable and accurate in-line weighing of large packages without stopping the conveyor or needing to recalibrate.  It can be configured with an FDA-approved food-grade belt – making it the ideal choice food products in bags, cases, or boxes.

Extrusion and mixing

Compounding blends a polymer matrix with additives to achieve specific properties, while extrusion shapes cosmetics and personal care products from development through manufacturing. Reliable extrusion and compounding tools help ensure that powders, films, and coatings meet desired physical and performance attributes.

 

Twin-screw extruders mix, compound, and process materials with controlled temperatures and shear rates to study thermal stability, degradation, and mechanical properties.

 

Lab-scale extruders support efficient trials, essential for optimizing polymer materials. Continuous processing tools accelerate formulation development while helping to ensure consistency and regulatory compliance.

Pharma 11 Parallel Twin-Screw Extruder

Streamline your cosmetic formulations with the Thermo Scientific Pharma 11 Parallel Twin-Screw Extruder, enabling efficient compounding from 20 g/h to 2.5 kg/h. Working seamlessly with an injection molding machine, it produces various specimens for comprehensive testing, characterizing, and optimizing new formulations. Facilitate rapid development and testing of makeup products, helping to ensure high-quality outcomes and an efficient process.

Pharma 16 Twin-Screw Extruder

Quickly develop cosmetic formulations with the Thermo Scientific Pharma 16 Twin-Screw Extruder. Switch between continuous hot melt extrusion (HME) and wet granulation (TSG), reducing time and effort compared to batch processes. Optimize parameters fast and easily scale up, transferring directly to larger systems. Its plug-and-play functionality, user-friendly controls, and minimal ingredient usage help ensure efficient, high-quality production.

Pharma 24 Twin-Screw Extruder

Enhance cosmetic processing with a compact design that saves clean room space and reduces utility consumption compared to batch processes. The high free volume screw design and lower ingredient usage minimize handling and exposure. Removable screws and liners help ensure easy cleaning. Compatible with process analytical technology (PAT), the Thermo Scientific Pharma 24 Twin-Screw Extruder offers consistent quality. It is ideal for solubility enhancement, modified release, and biomedical products, with seamless integration into production lines. 

Fourier transform infrared (FTIR) spectroscopy

Fourier transform infrared (FTIR) spectroscopy is the preferred method of infrared spectroscopy. When IR radiation is passed through a sample, some radiation is absorbed by the sample and some passes through (is transmitted). The resulting signal at the detector is a spectrum representing a molecular ‘fingerprint’ of the sample. The usefulness of infrared spectroscopy arises because different chemical structures (molecules) produce different spectral fingerprints.

 

FTIR spectroscopy is a powerful analytical technique used to analyze materials across a broad range of industries, including cosmetics and personal care products. One specific use is to detect Phthalates, which are chemical compounds commonly found in cosmetics, particularly in products like nail polish, hairspray, perfumes, and lotions, where they act as plasticizers to add flexibility and help fragrances last longer; however, concerns exist regarding their potential health effects, especially related to endocrine disruption, making "phthalate-free" cosmetics a growing trend. 

 

Our FTIR microscopes extend analysis capabilities down to minute particles for contaminant analysis or microplastic applications.

Nicolet Summit FTIR Spectrometers

Thermo Scientific Nicolet Summit FTIR Spectrometers generate fast, reliable answers with less effort—even in busy, multi-user QC labs or teaching labs—with our compact, powerful FTIR technology from the name you trust in FTIR: Nicolet. You can rely on our compact benchtop spectrometers to help you confidently identify, verify, or quantify materials faster than ever before.

Nicolet Apex FTIR Spectrometer

Designed for both routine analysis and research applications, the Thermo Scientific Nicolet Apex FTIR Spectrometer offers exceptional performance and versatility. From routine quality control (QA/QC) to research and development, the Nicolet Apex Spectrometer is built to innovate, increase productivity, improve precision, and comply with extensive regulations.

Nicolet iS50 FTIR Spectrometer

Solve your analytical challenges with unmatched simplicity. Move from one experiment to another with the push of a button, integrating diamond ATR, Raman, and NIR. The Thermo Scientific Nicolet iS50 FTIR Spectrometer is ideal for polymer method development, troubleshooting, deformulation, and research.

Nicolet RaptIR+ FTIR Microscope

Extend the capabilities of the Nicolet iS20 or iS50 FTIR Spectrometer with the Thermo Scientific Nicolet RaptIR+ FTIR Microscope. Specialists and novice users alike can analyze samples more quickly with increased data capabilities, improved AI, an automated find and zoom function, higher optical resolution, and more.

Nicolet iN10 FTIR Microscope

Visually and chemically analyze your samples with this powerful combination of optical microscope with integrated FTIR spectroscopy. The Thermo Scientific Nicolet iN10 Microscope is ideal for small particle identification or high spatial resolution polymer characterization needs.

Metal detection

Metal detectors used in the personal care and cosmetics industry can find small particles of ferrous, non-ferrous, and stainless steel by passing the product through a detector containing coils wound on a non-metallic frame and connected to a high-frequency radio transmitter. When a particle of metal passes through the coils, the high frequency field is disturbed under one coil, changing the voltage by a few microvolts.

 

To improve sensitivity and enable the detection of many metal types and smaller sizes, we offer multiscan technology. Metal detectors with multiscan technology utilize up to five completely adjustable frequencies to find metal types and sizes previously undetectable. Using a true broad-spectrum approach reduces the probability of an escape by many orders of magnitude. This technology is analogous to having up to five metal detectors sequentially in a production line.

Sentinel Multiscan and Selectscan Metal Detectors

The Thermo Scientific Sentinel family of metal detectors provides high sensitivity detection performance to increase the probability of finding ferrous, non-ferrous, and stainless steel metal contaminants in food, beverage, and other products. The Sentinel 5000 Multiscan metal detection platform can scan a combination of up to five user-selectable frequencies to find all random sizes, shapes, and types of metal foreign objects.

Conveyors for Metal Detectors

Thermo Scientific Quickfit Metal Detector Conveyors are suitable for most food packaging and bulk flow metal detection applications. They can be engineered for the most demanding applications and come with options for inclines, flap/drop gates, retracting belts rejects, and a heavy duty (HD) drive for large products. The Customfit conveyor can be upgraded to IP69K washdown with enhanced sanitation options.

APEX 300 Flexible Metal Detector

The Thermo Scientific APEX 300 Flexible Metal Detector is designed with increased sensitivity, is compact, easy-to-install, and can be customized to fit your drop through, pipeline, and check weighing needs.

Near-infrared spectroscopy (NIR)

Near-infrared spectroscopy (NIR) is a non-destructive spectroscopic method that uses the near-infrared region of the electromagnetic spectrum, NIR is based on overtones and combinations of bond vibrations in molecules. NIR can typically penetrate much further into a sample than FTIR, and unlike Raman, is not affected by fluorescence. Thus, although NIR spectroscopy is not as chemically specific as Raman or FTIR, it can be very useful in probing bulk material with little or no sample preparation. It is a widely used rapid alternative to time-consuming, solvent intensive, wet-chemistry methods and chromatographic techniques. 

 

Our instruments help you to quickly verify incoming raw materials, monitor reaction progress, and quantify final products at reduced cost and increased sample throughput. 

Antaris II FT-NIR Analyzer

Easily implement laboratory-based FT-NIR performance in a ready-for-plant package using the Thermo Scientific Antaris II FT-NIR Analyzer. With industry-leading method transfer performance, the Antaris II FT-NIR Analyzer provides robust and reliable data collection for at-line, online and in-line analysis.

Antaris MX FT-NIR Process Analyzer

Optimize your QC testing while remotely monitoring the process using fiber optic simultaneous multiplexing technology and integrated communication for real-time feedback with the rugged Thermo Scientific Antaris MX FT-NIR process analyzer.

Process mass spectrometry

Process mass spectrometers analyze the composition of gases in real-time for industrial processes. They operate by ionizing gas molecules using an electron beam. These ions are then accelerated and passed through a magnetic or electric field, which separates them based on their mass-to-charge (m/z) ratio.

 

The separated ions hit a detector, generating a signal proportional to their abundance. By analyzing these signals, the mass spectrometer provides a detailed composition of the gas mixture. This data helps in monitoring and optimizing processes, ensuring product quality and safety in industries such as petrochemicals, pharmaceuticals, and environmental monitoring.

Prima PRO Process Mass Spectrometer

The Thermo Scientific Prima PRO Process Mass Spectrometer is an online mass spectrometer and process gas analyzer that provides fast, accurate, comprehensive gas analysis.  Engineered to meet a number of challenging process applications, including fermentation for the production of cosmetics and skincare, it delivers fast, complete, lab quality online gas composition analysis and features a rugged, fault-tolerant design that ensures availability that exceeds 99.7%. 

Prima BT Bench Top Process Mass Spectrometer

Gather respiratory gas data from multiple fermenters and bioreactors with a single analyzer, packaged ideally for development laboratories. The Thermo Scientific Prima BT Bench Top Process Mass Spectrometer is a precise, multi-stream magnetic sector mass spectrometer. Use this solution to monitor fermentations and cell cultures as part of your PAT implementation strategy, building a platform to reduce off-line testing while improving process understanding.

Raman spectroscopy

Raman spectroscopy is an analytical technique used to observe vibrational, rotational, and other low-frequency modes in a system. It relies on the inelastic scattering of monochromatic light, usually from a laser. When light interacts with molecular vibrations or other excitations in the material, the energy of the laser photons is shifted up or down, providing information about the vibrational modes of the molecules.

 

This technique is valuable for characterizing molecular structures, identifying substances, and studying molecular interactions. Raman spectroscopy is particularly useful for its ability to provide detailed information about molecular vibrations and the chemical composition of a sample without requiring extensive sample preparation.

 

With the Thermo Scientific DXR3 family of Raman instruments, you can quickly create research-grade chemical images—giving you instant information on the chemical, structural, and elemental characteristics of your sample.

DXR3 Raman Microscope

Analytical services labs are often staffed with scientists and technicians who must be able to walk up to any piece of equipment and get results without technique expertise. Optimization algorithms and automated system setup make the Thermo Scientific DXR Raman Microscope easy to approach and enables a non-specialist to generate excellent results.

TruScan G3 Handheld Raman Analyzer

The portable Thermo Scientific TruScan G3 Handheld Raman Analyzer helps the cosmetics industry meet GMP compliance by providing rapid, on-the-spot material identity verification specificity on tested raw materials. These easy-to-use handheld devices can be utilized anywhere in the facility, offering a fast return on investment through rapid implementation and savings generated from non-sampling activities. They enable identity testing through packaging, increasing the speed of analysis, and require minimal training for routine measurements, with no consumables needed. 

Rheology

In cosmetics and skincare, precise rheological measurements help ensure product performance and compliance with standards. Our rotational rheometer platforms facilitate comprehensive analysis, from R&D to quality control, aiding the development of innovative and high-quality products. 

 

Rheology is essential for understanding the mechanical properties of cosmetics. It examines how complex fluids and soft solids respond to stress, strain, and deformation. This insight helps control and predict the flow behavior and stability of products like polymers, gels, and emulsions. 

 

Polymers exhibit intricate flow behavior due to their chemical structure and high molecular weight. Determining their viscoelastic properties is crucial for optimizing formulations and production processes in cosmetic applications.

HAAKE Viscotester iQ Rheometers

Measure and analyze the rheological properties of a wide range of liquid, paste and semi-solid samples.  Thermo Scientific HAAKE Viscotester iQ Rheometers set new standards in modularity, ease of use, increased efficiency, and intelligent user guidance, from simple viscosity determinations to complex rheological investigations.

HAAKE MARS Rheometers

The Thermo Scientific HAAKE MARS Rheometer is a highly flexible Modular Advanced Rheometer System (MARS) that provides accuracy, easy handling, and many application-oriented solutions, including cosmetics, for comprehensive material characterization. Connect Assist functionality allows for effortless, error-free exchange of measuring geometries and temperature modules to speed up your workflow.

Powder Rheology Accessories for HAAKE MARS Rheometers

The Thermo Scientific Powder Rheology Accessories for HAAKE MARS Rheometers provide a comprehensive solution for analyzing powder flowability, compressability, and other powder properties. Designed for versatility and precision, these accessories support a wide range of applications and deliver valuable insights into powder behavior.

X-ray diffraction

X-ray diffraction (XRD) is a key analytical method in cosmetics development and quality control. It examines product formulations at the atomic level without damaging samples, making it ideal for analysing nanoparticles in skincare products and sunscreens. XRD helps manufacturers understand the crystalline structures that affect product performance and stability. By measuring particle size, phase composition, and lattice arrangement, XRD ensures product consistency, identifies counterfeits, and verifies ingredient quality. This technique ultimately supports both product effectiveness and consumer safety in the cosmetics industry.

ARL X'TRA Companion X-ray Diffractometer

Advanced benchtop X-ray diffractometer. Thermo Scientific ARL X’TRA Companion is a θ/θ Bragg-Brentano benchtop X-ray diffractometer perfectly suited for routine analysis thanks to an innovative configuration, using the latest technical features to grant accuracy, precision, safety and ease of use.

X-ray fluorescence

X-ray fluorescence (XRF) spectroscopy is a non-destructive analytical technique used to determine the elemental composition of materials. XRF analyzers work by measuring the fluorescent (or secondary) X-rays emitted from a sample getting irradiated by a primary X-ray source. Each of the elements present in a sample produces a set of characteristic fluorescent X-rays lines like a fingerprint.  These fingerprints are distinct for each element, making XRF spectroscopy an excellent tool not only for qualitative analysis but also for quantitative measurements when processing the intensity of the emitted lines. Lipsticks and other cosmetics have been found to contain lead, and with handheld XRF testing, users can help ensure their manufacturing programs are fully compliant while realizing significant improvements in the production process.

 

A convenient front-end analysis tool, EDXRF (energy-dispersive XRF) enables quick and easy analysis of even irregular samples with little-to-no sample preparation. WDXRF (wavelength-dispersive XRF), meanwhile, is the standard test method for a wide range of applications due to its outstanding sensitivity and high resolution.

Niton XL5 Plus Handheld XRF Analyzer

The Thermo Scientific Niton XL5 Plus Handheld XRF Analyzer delivers accurate metal analysis for verification of metals in manufacturing operations. Innovative design allows for instant, actionable data for quick decision making in critical situations. With an easy-to-use interface, portable analyzers provide rapid, reliable chemical identification and material verification in virtually any location.

Niton XL2 Plus Handheld XRF Analyzer

Confidently perform elemental analysis with the Thermo Scientific Niton XL2 Plus Handheld XRF Analyzer. Identify lead in paint and screen hazardous substances in consumer goods as this handheld instrument provides operators the ability to scan a broad range of materials in one versatile analyzer.

ARL PERFORM'X Sequential X-Ray Fluorescence Spectrometer

Analyze critical trace elements in polymers with high sensitivity and low limits of detection across the periodic table with the Thermo Scientific ARL PERFORM'X WDXRF Spectrometer which allows bulk analysis as well as advanced elemental mapping and spotting down to 0.5 mm. It is an excellent solution for demanding quantitative polymer analysis.

ARL QUANT'X EDXRF Spectrometer

Identify and quantify the elemental composition and concentrations of inorganic additives such as pigments, fillers, flame retardants and stabilizers in the polymer. The Thermo Scientific ARL QUANT'X EDXRF Spectrometer is ideally suited to analyze and quantify various elements down to sub-ppm levels to comply with the different norms.

FlashSmart Elemental Analyzer

Determine nitrogen, carbon, hydrogen, sulfur and oxygen in the material characterization and quality control testing of polymers with the Thermo Scientific FlashSmart Elemental Analyzer. Its automation and modularity help labs improve productivity over traditional methods without the use of hazardous reagents.

X-ray inspection

X-ray scanning offers the personal care products processing industry excellent versatility and functionality in product inspection.  X-ray inspection systems can detect a wide variety of metallic and non-metallic contaminants, but also deliver additional quality control capabilities, including the detection of missing product pieces and components, under- and over-fills, and other quality problems. 

 

Scanning systems using X-ray technology pass high energy, short wavelength light waves through the entire process stream.  As an X-ray penetrates the materials, it loses energy depending on the density of the materials it passes through.  Detectors capture the changes in the X-ray's energy and convert these signals into a grayscale image showing variations in material density. Analysis of this image can detect contaminants, inconsistencies within the product itself, packaging problems, and more. 

X-ray inspection systems in the cosmetics and personal care industry do not use radioactive materials to generate X-rays, instead they use high voltage X-ray tubes to generate power. When the tube is turned off, no X-ray energy is emitted.

 

Because X-ray inspection systems scan the entire product stream, they are useful for more than just detecting contaminants. They can greatly enhance quality control and help to ensure product safety.

NextGuard X-Ray Detection Systems

Thermo Scientific NextGuard X-ray Detection Systems are designed for a wide variety of applications to help find metallic and non-metallic foreign objects and ignore "wet" product effects caused by salt and moisture content, which is proven to be challenging with metal detectors.  They also offer enhanced capabilities to inspect packaged products for missing pieces or components, under- and over-fills, and other quality problems.

Xpert Sideshoot X-ray Inspection System

Thermo Scientific Xpert Sideshoot X-ray Inspection System helps meet the challenge of detecting foreign objects anywhere in cans and bottles.  They are high speed, high performance horizontal X-ray beam (back to front) systems that provide single beam X-ray inspection for tall, upright packages and include software specifically tailored to detect objects in all regions of cans and bottles.

Xpert Heavy Duty X-ray Inspection Systems

Thermo Scientific Xpert Heavy Duty X-ray Inspection Systems are high-power, robust solutions designed for maximum penetration through large, dense products. They easily detect a wide range of foreign materials in larger cases, bags and trays. They can be optionally upgraded to meet IP69K washdown specifications.

Xpert Conveyor X-Ray Inspection Systems

Thermo Scientific Xpert Conveyor X-Ray Inspection Systems are high performance vertical X-ray beam (top down) systems that perform X-ray contaminant detection and product inspection for bags, boxes, and other flat packages. Xpert Conveyor systems meet HACCP and retailer food safety and quality requirements, can be configured for any application or challenging factory environment, and include powerful software to eliminate false rejects. They can be upgraded to meet IP69K washdown specifications.

X-ray photoelectron spectroscopy (XPS)

X-ray photoelectron spectroscopy (XPS), also known as electron spectroscopy for chemical analysis (ESCA), is a highly surface-sensitive, quantitative, chemical analysis technique that can be used to solve a wide range of materials problems. XPS is the measurement of photoelectrons ejected from the surface of a material that has been irradiated with X-rays. The kinetic energy of the emitted photoelectrons is measured. This energy is directly related to the photoelectrons’ binding energy within the parent atom and is characteristic of the element and its chemical state.

 

Only electrons generated near the surface can escape without losing too much energy for detection. This means that XPS data is collected from the top few nanometers of the surface. It is this surface selectivity, coupled with quantitative chemical state identification, that makes XPS so valuable in a vast array of application areas.

 

Our XPS instruments help you understand the distribution of chemistries across a surface, for finding the limits of contamination, or even examining the thickness variation of an ultra-thin coating.

K-Alpha X-ray Photoelectron Spectrometer (XPS) System

Get precise results, quickly and efficiently. The compact Thermo Scientific K-Alpha X-ray Photoelectron Spectrometer (XPS) System bridges the XPS requirements for both research and routine analysis with high sample throughput and advanced capabilities. Intuitive operation, guided by the Thermo Scientific Avantage Data System, makes the K-Alpha XPS System ideal for multi-user facilities.

For Research Use Only. Not for use in diagnostic procedures.