two scientists at a table pipetting solutions

Collaborating to accelerate your discovery

Advanced design and viral production services enable you to move forward toward your next discovery. From design, synthesis, and  production of viral particles, we offer end-to-end services to support every step in your lentivirus (LV) and Adeno-associated virus (AAV) RUO production. Our dedicated staff of R&D scientists and project managers are ready to partner with you and your colleagues to help accelerate your research program. If you’re looking for larger-scale production or seeking CDMO guidance on virus production, see the service guide for other options.

Lentivirus and Adeno-Associated Virus RUO production available

  • We offer a complete end-to-end service for the creation of lentiviral and adeno-associated virus expression constructs and virus packaging
  • Packaged and titered virus, ready in as little as 4 weeks
  • Different promoters and selection markers available for maximum flexibility for transfer plasmid construction
     

Overview of RUO virus production process

Process diagram showing steps from plasmid development and virus production to purification, QC, and delivery to customer.

Viral production workflow

  • 100 mL production scale (please inquire for production scale of up to 1L)
  • Uses Gibco LV-MAX or AAV-MAX system CTS-grade for easy scale-up
  • Packaged virus particles can be concentrated up to 100X
  • Titer determined by p24 ELISA for Lentivirus or qPCR for AAV
  • Optional functional titer of viral particles available as a separate assay
  • Final deliverable: concentrated virus particles, 1 mL (5 x 200 µL) with an average titer range between 106–10for lentivirus and 109–1012 for AAV
  • 100 mL production scale (please inquire for production scale of up to 1L)
  • Uses Gibco LV-MAX or AAV-MAX system CTS-grade for easy scale-up
  • Packaged virus particles can be concentrated up to 100X
  • Titer determined by p24 ELISA for Lentivirus or qPCR for AAV
  • Optional functional titer of viral particles available as a separate assay
  • Final deliverable: concentrated virus particles, 1 mL (5 x 200 µL) with an average titer range between 106–10for lentivirus and 109–1012 for AAV

Viral production depends on advanced technologies

The Gibco Lentiviral Production systems are the first optimized systems that provide all the high-quality components you need in a chemically defined, serum-free environment.

Gibco AAV Max Helper-Free AAV Production System Kit

AAV-MAX is a scalable, high-titer platform for suspension AAV production that can help enable you to seamlessly transition from discovery to commercial production.

  • High AAV titers
  • Scalability
  • Animal origin–free (AOF)
  • Clonal 293F-derived producer cells

Learn more

bottles and vials that make up the AAV-MAX Helper-Free AAV Production System Kit

Gibco LV-MAX Lentiviral Production System

LV-MAX is designed to seamlessly transition from discovery to commercial production, offering a scalable and high-yield lentiviral production platform. It is a suspension based, high-density culture of HEK 293–derived Viral Production Cells adapted to a special chemically defined, serum-free and protein-free LV-MAX Production Medium.

  • High titers
  • Scalability
  • Animal origin–free (AOF)

Learn more

bottle and vials for the LV-MAX Lentiviral Production System

Discover the right partner for your virus production needs

 

Cell Biology Services

Translational Services

Patheon Services

Description

Lentivirus or Adeno-associated virus vector design and packaging services. Research use only.

Lentivirus and Adeno-associated virus production using scalable platform manufacturing processes, enabling transition to GMP manufacturing.

Suitable for in vivo and ex vivo use. Not intended for IND-enabling applications.

CDMO partner from process and analytical development to GMP clinical and commercial supply of viral vectors.

Development phase

  • Research and development
  • Early lead identification
  • Lead identification
  • Proof of concept
  • Discovery
  • Pre-clinical
  • Clinical
  • Commercial

CDMO strategy

  • In-house GMP manufacturing
  • Established non-Thermo Fisher CDMO partnership
  • Undecided on CDMO strategy
  • Seeking partnership or CDMO guidance

Seeking partnership or CDMO guidance

Capacity/volume

Up to 2 liters

Up to 10 liters

Up to 2,000 liters

Regulatory assistance provided

No

Yes, limited

Yes

Additional information

Contact us

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Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.