Virus Production Media & Reagents

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Enhance vaccine production with virus production media

Vaccine manufacturers face increasing pressure to meet safety, yield, and regulatory expectations while moving from development to production on tight timelines. Serum variability, raw-material uncertainty, and complex culture conditions can introduce risk and slow advancement. Gibco virus production media and reagents are designed to help researchers establish reproducible environments for viral growth and vaccine production. With defined formulations that support common cell lines, these media help maintain stable performance from early development through cGMP manufacturing.

Benefits of Gibco vaccine production media

Gibco vaccine production media are developed to support reproducible virus expression and consistent performance across vaccine manufacturing workflows. Defined, serum-reduced, and animal origin-free (AOF) options help scientists manage variability while maintaining yield and quality.

Our Gibco vaccine production media are designed to:

  • Reduce manufacturing risk and variability linked to serum use
  • Support widely used cell lines, including Vero, MDCK, HEK 293, BHK-21, MDBK, and Sf9/12
  • Maintain performance from early development to large-scale production
  • Simplify the transition to serum-reduced or animal origin-free conditions

Enable vaccine innovation with virus production media

Scaling a vaccine process often exposes gaps in consistency that can slow development or require unplanned adjustments. Defined Gibco virus production media and virus growth media help limit these differences, supporting predictable cell behavior and stable virus expression at each stage. These formulations are used across viral platforms, including adeno-associated virus (AAV) and lentivirus (LV) systems, allowing process teams to apply familiar methods when working in both vaccine and viral vector production. With clear documentation and reliable lot-to-lot control, these media support easy comparison of results, qualification of materials, and advancement of vaccine programs with few process changes.

Ordering information

货号 产品名称 规格 Price 数量
12309019 OptiPRO™ SFM, 1000 mL Each
2,263.00
A4000164001 OptiPRO™ SFM AGT™ Medium, 10 L 10 L
8,368.32
A4000164002 OptiPRO™ SFM AGT™ Medium, 100 L 100 L
57,328.21

货号 产品名称 规格 Price 数量
11681020 VP-SFM (1X) Each
1,754.00

货号 产品名称 规格 Price 数量
A1627703 CD BHK-21 Production Medium, 10 kg Each
47,235.00

货号 产品名称 规格 Price 数量
12529012 CD 293 AGT™ Medium, 10 L Each
14,976.00

货号 产品名称 规格 Price 数量
12658035 Sf-900™ III SFM, 10 L Each
16,999.00

Help minimize serum with supplements and reagents

Serum can introduce variability that affects vaccine yield and complicates processes. Gibco TrypLE Select, Gibco GlutaMAX Supplement, and Gibco AlbuMAX Lipid-Rich BSA support cell growth without the variability associated with serum. Using these reagents helps maintain cell health and lot-to-lot consistency, supporting a gradual shift toward serum-reduced or animal origin-free conditions while maintaining process stability.

Ordering information

货号 产品名称 规格 Price 数量
35050061 GlutaMAX™ Supplement, 100 mL Each
807.00

货号 产品名称 规格 Price 数量
11021029 AlbuMAX™ II Lipid-Rich BSA, 25 g Each
6,620.00
11020021 AlbuMAX™ I Lipid-Rich BSA, 25 g Each
2,132.00

Explore other media for consistent cell growth

Many vaccine and therapeutic processes rely on cell culture systems that perform consistently at every scale. Gibco cell culture media are prepared under defined conditions so that cell behavior stays predictable from early testing through manufacturing.

CHO media


Gibco CHO media support consistent cell growth and protein expression from development through manufacturing. Serum-free and chemically defined formulations help maintain performance and product quality across scales.

Diploid cell culture media for vaccines

Gibco diploid cell media enhance reliable growth and attachment for lines such as MRC-5, WI-38, and chicken embryo fibroblasts. Serum-reduced and defined options optimize performance from development to cGMP production.

Explore end-to-end vaccine bioprocessing solutions

Thermo Fisher Scientific connects upstream and downstream steps in vaccine manufacturing to help teams maintain process reliability from research to commercial scale. Integrated solutions span cell expansion, virus expression, purification, and scale-up, supported by technical experience and global manufacturing capabilities. These connected workflows enable consistent performance and help simplify qualifications in cGMP environments.
 

Discover other cell culture solutions to scale vaccine processes


Scaling vaccine production requires consistent performance and flexible solutions across upstream and downstream operations. Thermo Fisher Scientific supports these needs with cell culture products designed to maintain yield and control variability. Explore complementary solutions such as feeds and supplements, functional additives and reagents, and bioreactors  to strengthen performance throughout your process.

 

Find the right media formulation for your process

Every vaccine process has specific performance and scale requirements. Thermo Fisher Scientific supports custom media development through Gibco Media by Design Services, helping teams define component and concentration specifications that align with their specific cell lines and manufacturing goals. Working directly with specialists can help maintain consistency, simplify documentation, and support a smooth transition from development to cGMP production.
 

Frequently asked questions

Virus production media enable defined conditions that support cell growth and virus replication for vaccine manufacturing. In some processes, the medium serves as the foundation for consistent performance by controlling nutrients, pH, and osmolality throughout development and scale-up.

Serum-free formulations help reduce variability and the risk of contamination from animal-derived materials. They can also simplify process verification and regulatory documentation by facilitating the use of a consistent, well-defined composition across production runs.

Vero, MDCK, HEK 293, BHK-21, MDBK, and Sf9/12 cell lines are routinely used for viral vaccine production. Each supports specific virus types and culture formats, and Gibco media are available for both adherent and suspension-based production.

Defined media can reduce the variability introduced by undefined ingredients such as serum or hydrolysates. With known component concentrations, defined media can help maintain stable culture conditions and support reproducible virus production across batches.

Classical media are suitable for use when a process depends on serum or legacy conditions. These formulations are produced under the same high manufacturing standards as recent media, supporting continuity in established vaccine workflows.

Viral vaccine resources

Find technical guidance and scientific materials to support each stage of vaccine process development. The Viral Vaccine Resource Hub includes application notes, case studies, webinars, and technical documents focused on cell culture, virus expression, and downstream processing.

Enable accelerated vaccine development with virus media

For research use or further manufacturing. Not for diagnostic use or direct administration into humans or animals.